COVID-19 Induced Acute Respiratory Distress Syndrome—A Multicenter Observational Study

Background: Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respiratory distress syndrome (ARDS). Methods: This is...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Frontiers in medicine Jg. 7; S. 599533
Hauptverfasser: Herrmann, Johannes, Adam, Elisabeth Hannah, Notz, Quirin, Helmer, Philipp, Sonntagbauer, Michael, Ungemach-Papenberg, Peter, Sanns, Andreas, Zausig, York, Steinfeldt, Thorsten, Torje, Iuliu, Schmid, Benedikt, Schlesinger, Tobias, Rolfes, Caroline, Reyher, Christian, Kredel, Markus, Stumpner, Jan, Brack, Alexander, Wurmb, Thomas, Gill-Schuster, Daniel, Kranke, Peter, Weismann, Dirk, Klinker, Hartwig, Heuschmann, Peter, Rücker, Viktoria, Frantz, Stefan, Ertl, Georg, Muellenbach, Ralf Michael, Mutlak, Haitham, Meybohm, Patrick, Zacharowski, Kai, Lotz, Christopher
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Switzerland Frontiers Media SA 18.12.2020
Frontiers Media S.A
Schlagworte:
Age
ARDS (acute respiratory distress syndrome)
Body mass index
Coronaviruses
COVID-19
Diabetes
Disease prevention
Disease transmission
Edema
Fatalities
Germany
Hypertension
Infections
Intensive care
intensive care medicine
Medicine
pandemia
Patients
Regression analysis
Respiratory distress syndrome
Severe acute respiratory syndrome
Software
Viruses
United States > US
Italy
Germany
COVID-19
pandemia
ARDS (acute respiratory distress syndrome)
intensive care medicine
Germany
ISSN:2296-858X, 2296-858X
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background: Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respiratory distress syndrome (ARDS). Methods: This is a retrospective, observational multicentre study in five German secondary or tertiary care hospitals. All patients consecutively admitted to the intensive care unit (ICU) in any of the participating hospitals between March 12 and May 4, 2020 with a COVID-19 induced ARDS were included. Results: A total of 106 ICU patients were treated for COVID-19 induced ARDS, whereas severe ARDS was present in the majority of cases. Survival of ICU treatment was 65.0%. Median duration of ICU treatment was 11 days; median duration of mechanical ventilation was 9 days. The majority of ICU treated patients (75.5%) did not receive any antiviral or anti-inflammatory therapies. Venovenous (vv) ECMO was utilized in 16.3%. ICU triage with population-level decision making was not necessary at any time. Univariate analysis associated older age, diabetes mellitus or a higher SOFA score on admission with non-survival during ICU stay. Conclusions: A high level of care adhering to standard ARDS treatments lead to a good outcome in critically ill COVID-19 patients.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
These authors share senior authorship
Reviewed by: Jesus Rico-Feijoo, Hospital Universitario Río Hortega, Spain; Tommaso Tonetti, University of Bologna, Italy
Edited by: Jiapeng Huang, University of Louisville, United States
This article was submitted to Intensive Care Medicine and Anesthesiology, a section of the journal Frontiers in Medicine
These authors share first authorship
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2020.599533