Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study
Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution o...
Uloženo v:
| Vydáno v: | Journal of critical care Ročník 27; číslo 3; s. 283 - 288 |
|---|---|
| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
Elsevier Inc
01.06.2012
Elsevier Limited |
| Témata: | |
| ISSN: | 0883-9441, 1557-8615, 1557-8615 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.
Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.
Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.
Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. |
|---|---|
| AbstractList | Abstract Purpose Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Methods Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scv o2 ] and central venous to arterial P co2 gradient [P(cv-a) co2 ]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Results Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation ( P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Conclusion Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.PURPOSEPerfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.METHODSPatients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.RESULTSForty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation.CONCLUSIONEarly recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. |
| Author | Pedreros, Cesar Kattan, Eduardo Romero, Carlos Ince, Can Bravo, Sebastian Neira, Rodolfo Hernandez, Glenn Rovegno, Maximiliano Castro, Ricardo Veas, Enrique Bruhn, Alejandro |
| Author_xml | – sequence: 1 givenname: Glenn surname: Hernandez fullname: Hernandez, Glenn email: glennguru@gmail.com organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 2 givenname: Cesar surname: Pedreros fullname: Pedreros, Cesar organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 3 givenname: Enrique surname: Veas fullname: Veas, Enrique organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 4 givenname: Alejandro surname: Bruhn fullname: Bruhn, Alejandro organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 5 givenname: Carlos surname: Romero fullname: Romero, Carlos organization: Unidad de Pacientes Críticos, Hospital Clínico Universidad de Chile, Santos Dumont 999, Santiago, Chile – sequence: 6 givenname: Maximiliano surname: Rovegno fullname: Rovegno, Maximiliano organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 7 givenname: Rodolfo surname: Neira fullname: Neira, Rodolfo organization: Unidad de Pacientes Críticos, Hospital Clínico Universidad de Chile, Santos Dumont 999, Santiago, Chile – sequence: 8 givenname: Sebastian surname: Bravo fullname: Bravo, Sebastian organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 9 givenname: Ricardo surname: Castro fullname: Castro, Ricardo organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 10 givenname: Eduardo surname: Kattan fullname: Kattan, Eduardo organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 11 givenname: Can surname: Ince fullname: Ince, Can organization: Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21798706$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkk9r3DAQxUVJaTZpv0APxdBLL3ZHsmRrSwmEkP6BQA9tz0KWx1ltvJYr2Qv-9pXYbAsLTU-C4ffeiPfmgpwNbkBCXlMoKNDq_bbYGm8KBpQWIApg_BlZUSHqXFZUnJEVSFnma87pObkIYQtA67IUL8g5o_Va1lCtyHK7d_08WTdkrstG9HbcoNd9tg_ZDifduN6aNO_mkKBRex3n6EPWzt4O91nAcYpI2DjzkHkMczB20smxyK4z09vBGt3n42aJBr27T-w0t8tL8rzTfcBXj-8l-fnp9sfNl_zu2-evN9d3ueFrmHImm4p3wE3bQYWampYbgQYbSbu2rk3VctpoaEQpjOhAm7rlIGtWVihNzaG8JO8OvqN3v2YMk9rZYLDv9YBuDipGKRjnlRARfXuCbt3sh_i7SJUl42VdJerNIzU3O2zV6O1O-0UdQ40AOwDGuxA8dn8QCmldpbYqNadScwqEis1FkTwRHWOcvLb909KPBynGGPcWvYoV4GCwtR7NpFpnn5ZfnciPpT3gguFvBCowBep7uqp0VJQCMCZTwh_-bfC_7b8BtUPeXQ |
| CitedBy_id | crossref_primary_10_1016_j_emc_2019_03_005 crossref_primary_10_1111_vec_12992 crossref_primary_10_1016_j_jss_2014_12_014 crossref_primary_10_1111_vec_13088 crossref_primary_10_1007_s00101_014_2335_6 crossref_primary_10_1007_s10877_020_00611_x crossref_primary_10_1186_s13613_021_00847_z crossref_primary_10_1186_s13613_022_01049_x crossref_primary_10_3389_fmed_2023_1218462 crossref_primary_10_1097_MCC_0000000000001038 crossref_primary_10_1080_23744235_2025_2543077 crossref_primary_10_1177_08850666211044124 crossref_primary_10_1186_cc12155 crossref_primary_10_1016_j_redare_2024_01_003 crossref_primary_10_1097_MCC_0000000000000194 crossref_primary_10_1186_s13613_016_0164_2 crossref_primary_10_1186_s13613_018_0398_2 crossref_primary_10_1016_j_medin_2017_03_008 crossref_primary_10_1093_trstmh_try007 crossref_primary_10_1016_j_iccn_2024_103743 crossref_primary_10_1186_s13613_017_0253_x crossref_primary_10_1007_s00134_014_3600_5 crossref_primary_10_1177_08850666231168038 crossref_primary_10_1371_journal_pone_0188548 crossref_primary_10_1038_jp_2017_57 crossref_primary_10_1097_01_NAJ_0000525851_44945_70 crossref_primary_10_1016_j_medine_2017_06_008 crossref_primary_10_3389_fmed_2020_614326 crossref_primary_10_1007_s10877_022_00946_7 crossref_primary_10_1007_s10015_021_00723_w crossref_primary_10_1016_j_resplu_2024_100845 crossref_primary_10_1186_s13613_020_00732_1 crossref_primary_10_1097_CM9_0000000000000221 crossref_primary_10_1016_j_cca_2021_06_021 crossref_primary_10_1186_s13054_016_1243_3 crossref_primary_10_1089_ars_2021_0027 crossref_primary_10_1016_j_jcrc_2016_05_007 crossref_primary_10_1097_CCM_0000000000004177 crossref_primary_10_3390_diagnostics15172252 crossref_primary_10_1096_fj_202401889R crossref_primary_10_3389_fmed_2020_612303 crossref_primary_10_1186_s13613_014_0030_z crossref_primary_10_1007_s10877_025_01324_9 crossref_primary_10_1111_1440_1681_13540 crossref_primary_10_1016_j_emc_2016_09_001 crossref_primary_10_1097_MEJ_0000000000000705 crossref_primary_10_1186_s13613_020_00767_4 crossref_primary_10_1016_j_redar_2023_07_006 crossref_primary_10_1007_s00134_013_2982_0 crossref_primary_10_1186_s13613_024_01275_5 crossref_primary_10_1016_j_medin_2019_09_009 crossref_primary_10_1097_MCC_0000000000000603 crossref_primary_10_1097_MCC_0000000000000403 crossref_primary_10_1016_j_heliyon_2024_e35716 crossref_primary_10_3389_fmed_2020_00291 crossref_primary_10_1177_0885066620982585 crossref_primary_10_1097_MCC_0000000000000495 crossref_primary_10_1016_j_ajem_2018_07_010 crossref_primary_10_1016_j_medine_2019_09_002 crossref_primary_10_1016_j_jcrc_2019_11_008 crossref_primary_10_1177_08850666241253162 crossref_primary_10_1186_s12887_020_02418_w crossref_primary_10_1186_s13613_019_0511_1 crossref_primary_10_1097_SHK_0000000000001066 crossref_primary_10_1007_s00134_018_5415_2 crossref_primary_10_1111_anae_12341 crossref_primary_10_3390_bioengineering10060729 crossref_primary_10_1007_s00134_014_3326_4 crossref_primary_10_1001_jama_2019_0071 crossref_primary_10_1097_CCM_0000000000006135 crossref_primary_10_1186_s12871_022_01920_1 crossref_primary_10_12677_NS_2021_106109 crossref_primary_10_1186_s13054_019_2589_0 crossref_primary_10_5005_jp_journals_10071_24586 crossref_primary_10_1097_SHK_0000000000000929 crossref_primary_10_1177_08850666211003507 crossref_primary_10_1186_s13054_019_2560_0 crossref_primary_10_1186_s40635_022_00473_4 crossref_primary_10_5005_jp_journals_10071_24301 |
| Cites_doi | 10.1056/NEJMoa010307 10.1007/s00134-007-0531-4 10.1186/cc5144 10.1186/cc2894 10.1186/cc8011 10.1097/MCC.0b013e32832b70e5 10.1097/00003246-199206000-00025 10.1097/CCM.0b013e31819869db 10.1016/j.resuscitation.2005.01.009 10.1007/s00134-008-1007-x 10.1007/s00134-007-0680-5 10.1097/01.ta.0000202062.49814.f4 10.1097/SHK.0b013e3181971d47 10.1097/01.CCM.0000050454.01978.3B 10.1016/j.ajem.2007.06.026 10.1016/S0002-9610(97)89552-9 10.1007/s00134-006-0118-5 10.1007/s00134-010-1970-x 10.1007/s00134-008-1199-0 10.1007/s00134-005-2790-2 10.1007/s00134-007-0934-2 10.1186/cc7802 10.1097/00005373-200104000-00005 10.1161/01.CIR.39.1.131 10.1016/S0140-6736(05)71045-X |
| ContentType | Journal Article |
| Copyright | 2012 Elsevier Inc. Elsevier Inc. Copyright © 2012 Elsevier Inc. All rights reserved. |
| Copyright_xml | – notice: 2012 Elsevier Inc. – notice: Elsevier Inc. – notice: Copyright © 2012 Elsevier Inc. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7RV 7X7 7XB 88E 8FI 8FJ 8FK 8G5 ABUWG AFKRA AN0 ASE AZQEC BENPR CCPQU DWQXO FPQ FYUFA GHDGH GNUQQ GUQSH K6X K9. KB0 M0S M1P M2O MBDVC NAPCQ PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS Q9U 7X8 |
| DOI | 10.1016/j.jcrc.2011.05.024 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Nursing & Allied Health Database Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni) ProQuest Central (Alumni) ProQuest Central UK/Ireland British Nursing Database British Nursing Index ProQuest Central Essentials - QC ProQuest Central ProQuest One ProQuest Central Korea British Nursing Index (BNI) (1985 to Present) Proquest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep (ProQuest) British Nursing Index ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Health & Medical Collection (Alumni) PML(ProQuest Medical Library) Research Library Research Library (Corporate) Nursing & Allied Health Premium Proquest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Research Library Prep ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Research Library ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest One Academic Eastern Edition British Nursing Index with Full Text British Nursing Index ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Research Library Prep MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7RV name: ProQuest Nursing & Allied Health Database url: https://search.proquest.com/nahs sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1557-8615 |
| EndPage | 288 |
| ExternalDocumentID | 2735080351 21798706 10_1016_j_jcrc_2011_05_024 S0883944111002280 1_s2_0_S0883944111002280 |
| Genre | Journal Article |
| GeographicLocations | Chile |
| GeographicLocations_xml | – name: Chile |
| GroupedDBID | --- --K --M -RU .1- .FO .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 2FS 354 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 7RV 7X7 88E 8FI 8FJ 8G5 8P~ 9JM AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAWTL AAXKI AAXUO AAYWO ABBQC ABFRF ABJNI ABMAC ABMZM ABUWG ABWVN ABXDB ACDAQ ACGFO ACGFS ACIEU ACLOT ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADFRT ADMUD ADNMO AEBSH AEFWE AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFKRA AFPUW AFRHN AFTJW AFXIZ AGHFR AGQPQ AGUBO AGYEJ AHHHB AHMBA AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ AN0 ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN AZQEC BENPR BKEYQ BKOJK BLXMC BNPGV BNQBC BPHCQ BVXVI C45 CCPQU CS3 DU5 DWQXO EBS EFJIC EFKBS EFLBG EJD EMOBN EO8 EO9 EP2 EP3 EX3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN FYUFA G-2 G-Q GBLVA GNUQQ GUQSH HDV HMCUK HMK HMO HVGLF HZ~ IHE J1W KOM LX1 M1P M29 M2O M41 MO0 N9A NAPCQ O-L O9- OA0 OAUVE OBH OHH OM- OVD OZT P-8 P-9 P2P PC. PHGZM PHGZT PJZUB PPXIY PQQKQ PROAC PSQYO Q38 R2- ROL RPZ SAE SDF SDG SEL SES SEW SPCBC SSH SSZ SV3 T5K TEORI UKHRP UNMZH UV1 WHG WOW WUQ Z5R ZB8 ZGI ZY1 ~G- ~HD 3V. AACTN AFCTW AFKWA AJOXV ALIPV AMFUW RIG AAIAV ABLVK ABYKQ AFDAS AJBFU LCYCR 9DU AAYXX AFFHD CITATION AGCQF AGRNS CGR CUY CVF ECM EIF NPM 7XB 8FK ASE FPQ K6X K9. MBDVC PKEHL PQEST PQUKI PRINS Q9U 7X8 |
| ID | FETCH-LOGICAL-c490t-28b64f04cdf06ea1cd4c5eceb81fd77c6d41ba0b535c5f0ac7d4087236e8c7403 |
| IEDL.DBID | BENPR |
| ISICitedReferencesCount | 95 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000304872000011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0883-9441 1557-8615 |
| IngestDate | Sun Nov 09 10:29:35 EST 2025 Sat Nov 29 14:23:09 EST 2025 Mon Jul 21 05:50:00 EDT 2025 Sat Nov 29 05:03:32 EST 2025 Tue Nov 18 20:51:51 EST 2025 Fri Feb 23 02:29:45 EST 2024 Sun Feb 23 10:19:23 EST 2025 Tue Oct 14 19:34:59 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | Septic shock Peripheral perfusion Lactate Resuscitation |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 Copyright © 2012 Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c490t-28b64f04cdf06ea1cd4c5eceb81fd77c6d41ba0b535c5f0ac7d4087236e8c7403 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Undefined-1 ObjectType-Feature-3 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| PMID | 21798706 |
| PQID | 1033243765 |
| PQPubID | 1226342 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_1015244655 proquest_journals_1033243765 pubmed_primary_21798706 crossref_primary_10_1016_j_jcrc_2011_05_024 crossref_citationtrail_10_1016_j_jcrc_2011_05_024 elsevier_sciencedirect_doi_10_1016_j_jcrc_2011_05_024 elsevier_clinicalkeyesjournals_1_s2_0_S0883944111002280 elsevier_clinicalkey_doi_10_1016_j_jcrc_2011_05_024 |
| PublicationCentury | 2000 |
| PublicationDate | 2012-06-01 |
| PublicationDateYYYYMMDD | 2012-06-01 |
| PublicationDate_xml | – month: 06 year: 2012 text: 2012-06-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Philadelphia |
| PublicationTitle | Journal of critical care |
| PublicationTitleAlternate | J Crit Care |
| PublicationYear | 2012 |
| Publisher | Elsevier Inc Elsevier Limited |
| Publisher_xml | – name: Elsevier Inc – name: Elsevier Limited |
| References | Lima, Bakker (bb0095) 2005; 31 Kaplan, McPartland, Santora, Trooskin (bb0055) 2001; 50 Lima, van Bommel, Jansen, Ince, Bakker (bb0130) 2009; 13 Bracht, Hänggi, Jeker, Wegmüller, Porta, Tüller (bb0035) 2007; 11 Dellinger, Levy, Carlet, Bion, Parker, Jaeschke (bb0010) 2008; 34 Vallée, Vallet, Mathe, Parraguette, Mari, Silva (bb0030) 2008; 34 Anderson, Kelly, Kerr, Clooney, Jolley (bb0105) 2008; 26 Rivers, Nguyen, Havstad, Ressler, Muzzin, Knoblich (bb0020) 2001; 345 Lima, Jansen, van Bommel, Ince, Bakker (bb0060) 2009; 37 Hernandez, Peña, Cornejo, Rovegno, Retamal, Navarro (bb0025) 2009; 13 Hernandez, Bruhn, Romero, Larrondo, De La Fuente, Cornejo (bb0075) 2006; 60 Spronk, Zandstra, Ince (bb0040) 2004; 8 Levy, Gibot, Franck, Cravoisy, Bollaert (bb0100) 2005; 365 Joly, Weil (bb0050) 1969; 39 Arnold, Shapiro, Jones, Schorr, Pope, Casner (bb0115) 2009; 32 Levy, Fink, Marshall, Abraham, Angus, Cook (bb0065) 2003; 31 Boerma, Ince (bb0125) 2010; 36 Hernandez, Castro, Romero, De la Hoz, Angulo, Aranguiz (bb0135) 2010 Hernandez, Bruhn, Romero, Javier Larrondo, De La Fuente, Castillo (bb0070) 2005; 66 Bakker, Gris, Coffernils, Kahn, Vincent (bb0120) 1996; 171 Sevransky (bb0110) 2009; 15 (bb0005) 1992; 20 Cornejo, Downey, Castro, Romero, Regueira, Vega (bb0080) 2006; 32 Howell, Donnino, Clardy, Talmor, Shapiro (bb0045) 2007; 33 Antonelli, Levy, Andrews, Chastre, Hudson, Manthous (bb0015) 2007; 33 Castro, Regueira, Aguirre, Llanos, Bruhn, Bugedo (bb0085) 2008; 74 Boerma, Kuiper, Kingma, Egbers, Gerritsen, Ince (bb0090) 2008; 34 Boerma (10.1016/j.jcrc.2011.05.024_bb0090) 2008; 34 Howell (10.1016/j.jcrc.2011.05.024_bb0045) 2007; 33 Kaplan (10.1016/j.jcrc.2011.05.024_bb0055) 2001; 50 Levy (10.1016/j.jcrc.2011.05.024_bb0065) 2003; 31 Dellinger (10.1016/j.jcrc.2011.05.024_bb0010) 2008; 34 Sevransky (10.1016/j.jcrc.2011.05.024_bb0110) 2009; 15 (10.1016/j.jcrc.2011.05.024_bb0005) 1992; 20 Anderson (10.1016/j.jcrc.2011.05.024_bb0105) 2008; 26 Bakker (10.1016/j.jcrc.2011.05.024_bb0120) 1996; 171 Spronk (10.1016/j.jcrc.2011.05.024_bb0040) 2004; 8 Joly (10.1016/j.jcrc.2011.05.024_bb0050) 1969; 39 Lima (10.1016/j.jcrc.2011.05.024_bb0130) 2009; 13 Lima (10.1016/j.jcrc.2011.05.024_bb0060) 2009; 37 Hernandez (10.1016/j.jcrc.2011.05.024_bb0135) 2010 Arnold (10.1016/j.jcrc.2011.05.024_bb0115) 2009; 32 Castro (10.1016/j.jcrc.2011.05.024_bb0085) 2008; 74 Boerma (10.1016/j.jcrc.2011.05.024_bb0125) 2010; 36 Bracht (10.1016/j.jcrc.2011.05.024_bb0035) 2007; 11 Rivers (10.1016/j.jcrc.2011.05.024_bb0020) 2001; 345 Antonelli (10.1016/j.jcrc.2011.05.024_bb0015) 2007; 33 Lima (10.1016/j.jcrc.2011.05.024_bb0095) 2005; 31 Levy (10.1016/j.jcrc.2011.05.024_bb0100) 2005; 365 Hernandez (10.1016/j.jcrc.2011.05.024_bb0025) 2009; 13 Hernandez (10.1016/j.jcrc.2011.05.024_bb0075) 2006; 60 Vallée (10.1016/j.jcrc.2011.05.024_bb0030) 2008; 34 Cornejo (10.1016/j.jcrc.2011.05.024_bb0080) 2006; 32 Hernandez (10.1016/j.jcrc.2011.05.024_bb0070) 2005; 66 |
| References_xml | – volume: 11 start-page: R2 year: 2007 ident: bb0035 article-title: Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study publication-title: Crit Care – volume: 32 start-page: 713 year: 2006 end-page: 722 ident: bb0080 article-title: High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock publication-title: Intensive Care Med – volume: 66 start-page: 63 year: 2005 end-page: 69 ident: bb0070 article-title: Management of septic shock with a norepinephrine-based haemodynamic algorithm publication-title: Resuscitation – volume: 13 start-page: S13 year: 2009 ident: bb0130 article-title: Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients publication-title: Crit Care – volume: 34 start-page: 1294 year: 2008 end-page: 1298 ident: bb0090 article-title: Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study publication-title: Intensive Care Med – volume: 26 start-page: 62 year: 2008 end-page: 65 ident: bb0105 article-title: Impact of patient and environmental factors on capillary refill time in adults publication-title: Am J Emerg Med – volume: 31 start-page: 1316 year: 2005 end-page: 1326 ident: bb0095 article-title: Noninvasive monitoring of peripheral perfusion publication-title: Intensive Care Med – year: 2010 ident: bb0135 article-title: Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? publication-title: J Crit Care – volume: 33 start-page: 575 year: 2007 end-page: 590 ident: bb0015 article-title: Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006 publication-title: Intensive Care Med – volume: 345 start-page: 1368 year: 2001 end-page: 1377 ident: bb0020 article-title: Early goal-directed therapy in the treatment of severe sepsis and septic shock publication-title: N Engl J Med – volume: 365 start-page: 871 year: 2005 end-page: 875 ident: bb0100 article-title: Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study publication-title: Lancet – volume: 13 start-page: R63 year: 2009 ident: bb0025 article-title: Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study publication-title: Crit Care – volume: 39 start-page: 131 year: 1969 end-page: 138 ident: bb0050 article-title: Temperature of the great toe as an indication of the severity of shock publication-title: Circulation – volume: 33 start-page: 1892 year: 2007 end-page: 1899 ident: bb0045 article-title: Occult hypoperfusion and mortality in patients with suspected infection publication-title: Intensive Care Med – volume: 15 start-page: 234 year: 2009 end-page: 238 ident: bb0110 article-title: Clinical assessment of hemodynamically unstable patients publication-title: Curr Opin Crit Care – volume: 171 start-page: 221 year: 1996 end-page: 226 ident: bb0120 article-title: Serial blood lactate levels can predict the development of multiple organ failure following septic shock publication-title: Am J Surg – volume: 50 start-page: 620 year: 2001 end-page: 627 ident: bb0055 article-title: Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients publication-title: J Trauma – volume: 34 start-page: 17 year: 2008 end-page: 60 ident: bb0010 article-title: Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 publication-title: Intensive Care Med – volume: 34 start-page: 2218 year: 2008 end-page: 2225 ident: bb0030 article-title: Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? publication-title: Intensive Care Med – volume: 60 start-page: 77 year: 2006 end-page: 81 ident: bb0075 article-title: Implementation of a norepinephrine-based protocol for management of septic shock: a pilot feasibility study publication-title: J Trauma – volume: 37 start-page: 934 year: 2009 end-page: 938 ident: bb0060 article-title: The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients publication-title: Crit Care Med – volume: 20 start-page: 864 year: 1992 end-page: 874 ident: bb0005 article-title: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis publication-title: Crit Care Med – volume: 32 start-page: 35 year: 2009 end-page: 39 ident: bb0115 article-title: Multi-center study of early lactate clearance as a determinant of survival in patients with presumed sepsis publication-title: Shock – volume: 8 start-page: 462 year: 2004 end-page: 468 ident: bb0040 article-title: Bench-to-bedside review: sepsis is a disease of the microcirculation publication-title: Crit Care – volume: 31 start-page: 1250 year: 2003 end-page: 1256 ident: bb0065 article-title: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference publication-title: Crit Care Med. – volume: 36 start-page: 2004 year: 2010 end-page: 2018 ident: bb0125 article-title: The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients publication-title: Intensive Care Med – volume: 74 start-page: 223 year: 2008 end-page: 231 ident: bb0085 article-title: An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock publication-title: Minerva Anestesiol – volume: 345 start-page: 1368 year: 2001 ident: 10.1016/j.jcrc.2011.05.024_bb0020 article-title: Early goal-directed therapy in the treatment of severe sepsis and septic shock publication-title: N Engl J Med doi: 10.1056/NEJMoa010307 – volume: 33 start-page: 575 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0015 article-title: Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006 publication-title: Intensive Care Med doi: 10.1007/s00134-007-0531-4 – volume: 11 start-page: R2 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0035 article-title: Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study publication-title: Crit Care doi: 10.1186/cc5144 – volume: 8 start-page: 462 year: 2004 ident: 10.1016/j.jcrc.2011.05.024_bb0040 article-title: Bench-to-bedside review: sepsis is a disease of the microcirculation publication-title: Crit Care doi: 10.1186/cc2894 – volume: 13 start-page: S13 issue: Suppl 5 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0130 article-title: Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients publication-title: Crit Care doi: 10.1186/cc8011 – volume: 15 start-page: 234 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0110 article-title: Clinical assessment of hemodynamically unstable patients publication-title: Curr Opin Crit Care doi: 10.1097/MCC.0b013e32832b70e5 – volume: 20 start-page: 864 year: 1992 ident: 10.1016/j.jcrc.2011.05.024_bb0005 article-title: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis publication-title: Crit Care Med doi: 10.1097/00003246-199206000-00025 – volume: 37 start-page: 934 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0060 article-title: The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients publication-title: Crit Care Med doi: 10.1097/CCM.0b013e31819869db – volume: 66 start-page: 63 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0070 article-title: Management of septic shock with a norepinephrine-based haemodynamic algorithm publication-title: Resuscitation doi: 10.1016/j.resuscitation.2005.01.009 – volume: 34 start-page: 1294 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0090 article-title: Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study publication-title: Intensive Care Med doi: 10.1007/s00134-008-1007-x – volume: 33 start-page: 1892 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0045 article-title: Occult hypoperfusion and mortality in patients with suspected infection publication-title: Intensive Care Med doi: 10.1007/s00134-007-0680-5 – volume: 60 start-page: 77 year: 2006 ident: 10.1016/j.jcrc.2011.05.024_bb0075 article-title: Implementation of a norepinephrine-based protocol for management of septic shock: a pilot feasibility study publication-title: J Trauma doi: 10.1097/01.ta.0000202062.49814.f4 – volume: 32 start-page: 35 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0115 article-title: Multi-center study of early lactate clearance as a determinant of survival in patients with presumed sepsis publication-title: Shock doi: 10.1097/SHK.0b013e3181971d47 – year: 2010 ident: 10.1016/j.jcrc.2011.05.024_bb0135 article-title: Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? publication-title: J Crit Care – volume: 31 start-page: 1250 year: 2003 ident: 10.1016/j.jcrc.2011.05.024_bb0065 article-title: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference publication-title: Crit Care Med. doi: 10.1097/01.CCM.0000050454.01978.3B – volume: 26 start-page: 62 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0105 article-title: Impact of patient and environmental factors on capillary refill time in adults publication-title: Am J Emerg Med doi: 10.1016/j.ajem.2007.06.026 – volume: 171 start-page: 221 year: 1996 ident: 10.1016/j.jcrc.2011.05.024_bb0120 article-title: Serial blood lactate levels can predict the development of multiple organ failure following septic shock publication-title: Am J Surg doi: 10.1016/S0002-9610(97)89552-9 – volume: 32 start-page: 713 year: 2006 ident: 10.1016/j.jcrc.2011.05.024_bb0080 article-title: High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock publication-title: Intensive Care Med doi: 10.1007/s00134-006-0118-5 – volume: 74 start-page: 223 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0085 article-title: An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock publication-title: Minerva Anestesiol – volume: 36 start-page: 2004 year: 2010 ident: 10.1016/j.jcrc.2011.05.024_bb0125 article-title: The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients publication-title: Intensive Care Med doi: 10.1007/s00134-010-1970-x – volume: 34 start-page: 2218 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0030 article-title: Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? publication-title: Intensive Care Med doi: 10.1007/s00134-008-1199-0 – volume: 31 start-page: 1316 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0095 article-title: Noninvasive monitoring of peripheral perfusion publication-title: Intensive Care Med doi: 10.1007/s00134-005-2790-2 – volume: 34 start-page: 17 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0010 article-title: Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 publication-title: Intensive Care Med doi: 10.1007/s00134-007-0934-2 – volume: 13 start-page: R63 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0025 article-title: Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study publication-title: Crit Care doi: 10.1186/cc7802 – volume: 50 start-page: 620 year: 2001 ident: 10.1016/j.jcrc.2011.05.024_bb0055 article-title: Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients publication-title: J Trauma doi: 10.1097/00005373-200104000-00005 – volume: 39 start-page: 131 year: 1969 ident: 10.1016/j.jcrc.2011.05.024_bb0050 article-title: Temperature of the great toe as an indication of the severity of shock publication-title: Circulation doi: 10.1161/01.CIR.39.1.131 – volume: 365 start-page: 871 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0100 article-title: Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study publication-title: Lancet doi: 10.1016/S0140-6736(05)71045-X |
| SSID | ssj0017335 |
| Score | 2.3064764 |
| Snippet | Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe... Abstract Purpose Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 283 |
| SubjectTerms | Aged Catheters Chile Critical Care Extremities - blood supply Female Fluid Therapy Heart rate Humans Lactate Lactic Acid - blood Male Microcirculation Middle Aged Monitoring, Physiologic - methods Multivariate Analysis Peripheral perfusion Prospective Studies Regional Blood Flow Resuscitation Sepsis Septic shock Shock, Septic - physiopathology Shock, Septic - therapy Skin Temperature Studies Toes - blood supply Veins & arteries |
| Title | Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0883944111002280 https://www.clinicalkey.es/playcontent/1-s2.0-S0883944111002280 https://dx.doi.org/10.1016/j.jcrc.2011.05.024 https://www.ncbi.nlm.nih.gov/pubmed/21798706 https://www.proquest.com/docview/1033243765 https://www.proquest.com/docview/1015244655 |
| Volume | 27 |
| WOSCitedRecordID | wos000304872000011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1557-8615 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017335 issn: 0883-9441 databaseCode: AIEXJ dateStart: 19950301 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVPQU databaseName: Health & Medical Collection (Proquest) customDbUrl: eissn: 1557-8615 dateEnd: 20251013 omitProxy: false ssIdentifier: ssj0017335 issn: 0883-9441 databaseCode: 7X7 dateStart: 20030301 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central Database Suite (ProQuest) customDbUrl: eissn: 1557-8615 dateEnd: 20251013 omitProxy: false ssIdentifier: ssj0017335 issn: 0883-9441 databaseCode: BENPR dateStart: 20030301 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Nursing & Allied Health Database customDbUrl: eissn: 1557-8615 dateEnd: 20251013 omitProxy: false ssIdentifier: ssj0017335 issn: 0883-9441 databaseCode: 7RV dateStart: 20030301 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: Research Library customDbUrl: eissn: 1557-8615 dateEnd: 20251013 omitProxy: false ssIdentifier: ssj0017335 issn: 0883-9441 databaseCode: M2O dateStart: 20030301 isFulltext: true titleUrlDefault: https://search.proquest.com/pqrl providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9swDCbWdhh22fvhtSs0YLfBhWzJlnIa2iHFDmtWdFuRmxDLEtoiTbo4CbB_P9KSvUubHnYx4IcsQaRIiqQ-AnyU0nPl8yzVaNymUnhcc5UTqau90zorrWtd2eff1Gikx-PBaXS4NTGtspOJraCu55Z85Li6hSDwvLL4fPM7papRFF2NJTS2YIeQypDPd46Go9OzPo6gRCixqbVIB6j547GZkOF1ZRc2gngWBzyXd6mmu0zPVgUdP_3fwT-DJ9H4ZIeBW57DAzd7AY9OYnj9JfwZriMnsrlnhIHcgg5M2bph126J_DK9tPTcr8jJxgg3_JryaRoWjjuyhpJkLGsuUMwy3MmvUMOGYP8BO2TdMcy09acEsctagNtX8Ot4-PPL1zTWZkitHPBlmuuqRDJLW3teuklma2kLZ12lM18rZctaZtWEV4UobOH5xKpacq1yUTptleTiNWzP5jP3Fpil47hV5gXtTdEa1VbWOGHOc-5pf5dA1pHFdGOm-hlT02WoXRkipSFSGl4YJGUCn_o2NwG2Y-PXoqO26WYCRahBrbKxlbqtlWuiFGhMZprccPOD2I-4j-D5CH4ogaJvGQ2dYMDc2-Nex17mXyc9byXwoX-NQoIiP5OZm6_oGzTTWqi8BN4EFu6nJSfIOsXLd5t_vguPcSR5yJLbg-3lYuXew0O7Xl42i33YUmfndB2r9qr340rEu5P8-1-3Pzp4 |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VgoALb0qggJHghFI5sRN7DwhV0KpVtyskCtqbu3Fs0Wq72653F_VP8RvxxHG40OXUA9ckfsT55mFn5huAt5xbKmyepdI7tyln1stcZVhqamukzEptmqPs730xGMjhsPdlDX7FXBgMq4w6sVHU9VTjGbmXbsaQPK8sPp5fpFg1Cv-uxhIaARYH5vKn37K5D_uf_fd9l-e7O0ef9tK2qkCqeY_O01xWpZ8g17WlpRlluua6MNpUMrO1ELqseVaNaFWwQheWjrSoOZUiZ6WRWnDKfL834KbX4wJLRYhht8HLBAsFPaVkac_7GW2STognO9Uz3VKGFls051cZwqsc3cbg7d7_35bqAdxrXWuyHWThIayZySO4fdgGDzyGy51lK2dkagkyPDeUCmOydOTMzL00jE80XrcLPEIkyIp-htFCjoRkTuIwBEgT98MbETIzbuH9hxDKsEW2SUwyTZvTomBUSEPf-wS-XcuLP4X1yXRingHRmGxcZZbhztv72lLz2n8gYym1uHtNIIswUHHOWB1krGL83alC6CiEjqKF8tBJ4H3X5jyQkqx8mkV0qbgS3kAobzNXthJ_a2Vcq-OcypTLFVVfEe6IdiQfRHKlBIquZevGBffsnyNuRjirP4N0WE7gTXfbq0D8rzWamOkCn_FOaEMEmMBGEJluWXIk5BO0fL6689dwZ-_osK_6-4ODF3DXzyoP8YCbsD6fLcxLuKWX8xM3e9VIPIHj65ab35YLlAw |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Nb9QwEB2Vgqpe-IYGChgJTijFiZ04e0Cool1Rtawq8aG9uRvHFq22u2Wzu6h_jV_HTByHC11OPXBN4sRx3sw8OzPPAK-kdFy5NIkLJLexFA5trrQitpWzRZHkxjZL2d-O1GBQDIe94zX4FWphKK0y-MTGUVdTQ2vkaN1CkHhenr11bVrE8V7__cWPmHaQoj-tYTsND5FDe_kTp2_1u4M9_Nav07S__-XDx7jdYSA2ssfncVqUOXZWmsrx3I4SU0mTWWPLInGVUiavZFKOeJmJzGSOj4yqJC9UKnJbGCW5wPvegJskKUhOQQ27yV6CxzLPYEXcQ87RFuz43LIzMzOtfGi2w1N5VVC8ivQ2wa9_538etrtwu6XcbNfbyD1Ys5P7sPGpTSp4AJf7y9b-2NQxUn5upBbGbFmzcztHKxmfGjruFrS0yEgt_ZyyiGrmizxZTalBhtXfMbiwma0XyCt8isMO22Wh-DRuVpF8sGGNrO9D-HotL_4I1ifTid0CZqgIuUycoBk5cvDCyAo_lnWcO5rVRpAESOjQZ9o1ZKxDXt6ZJhhpgpHmmUYYRfCma3PhxUpWXi0C0nQYCQwcGmPpylbqb61s3fq-Wie6TjXXnwn6hHwSJSTRpQiyrmVL7zxt--cTtwO09Z-HdLiO4GV3Gl0j_e8aTex0QdcgOW0EAiN47M2nG5aUhPoUz5-svvkL2EBz0UcHg8OnsImdSn2a4Dasz2cL-wxumeX8tJ49b4yfwcl1m81vDOCcyA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Evolution+of+peripheral+vs+metabolic+perfusion+parameters+during+septic+shock+resuscitation.+A+clinical-physiologic+study&rft.jtitle=Journal+of+critical+care&rft.au=Hernandez%2C+Glenn&rft.au=Pedreros%2C+Cesar&rft.au=Veas%2C+Enrique&rft.au=Bruhn%2C+Alejandro&rft.date=2012-06-01&rft.pub=Elsevier+Limited&rft.issn=0883-9441&rft.eissn=1557-8615&rft.volume=27&rft.issue=3&rft.spage=283&rft_id=info:doi/10.1016%2Fj.jcrc.2011.05.024&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=2735080351 |
| thumbnail_m | http://cvtisr.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F08839441%2FS0883944111X00102%2Fcov150h.gif |