Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study
Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution o...
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| Published in: | Journal of critical care Vol. 27; no. 3; pp. 283 - 288 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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United States
Elsevier Inc
01.06.2012
Elsevier Limited |
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| ISSN: | 0883-9441, 1557-8615, 1557-8615 |
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| Abstract | Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.
Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.
Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.
Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. |
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| AbstractList | Abstract Purpose Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Methods Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scv o2 ] and central venous to arterial P co2 gradient [P(cv-a) co2 ]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Results Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation ( P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Conclusion Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.PURPOSEPerfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject.Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.METHODSPatients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O(2) saturation [Scvo(2)] and central venous to arterial Pco(2) gradient [P(cv-a)co(2)]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours.Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.RESULTSForty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized.Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation.CONCLUSIONEarly recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe temperature difference (Tc-toe) have been proposed as objective reproducible parameters to evaluate peripheral perfusion. The comparative evolution of peripheral vs metabolic perfusion parameters in septic shock resuscitation has not been studied. We conducted a prospective observational clinical-physiologic study to address this subject. Patients with sepsis-related circulatory dysfunction were resuscitated according to a standard local algorithm. Perfusion assessment included serial determinations of metabolic (central venous O2 saturation [Scvo2] and central venous to arterial Pco2 gradient [P(cv-a)co2]) and peripheral perfusion parameters (CRT and Tc-toe, among others). Successful resuscitation was defined as a normal plasma lactate at 24 hours. Forty-one patients were included. The presence of normal values for both CRT and Tc-toe considered together at 6 hours was independently associated with a successful resuscitation (P = .02), as compared with the behavior of metabolic parameters. Capillary refill time was the first parameter to be significantly normalized. Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients. Our findings support the inclusion of serial peripheral perfusion assessment in multimodal monitoring strategies for septic shock resuscitation. |
| Author | Pedreros, Cesar Kattan, Eduardo Romero, Carlos Ince, Can Bravo, Sebastian Neira, Rodolfo Hernandez, Glenn Rovegno, Maximiliano Castro, Ricardo Veas, Enrique Bruhn, Alejandro |
| Author_xml | – sequence: 1 givenname: Glenn surname: Hernandez fullname: Hernandez, Glenn email: glennguru@gmail.com organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 2 givenname: Cesar surname: Pedreros fullname: Pedreros, Cesar organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 3 givenname: Enrique surname: Veas fullname: Veas, Enrique organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 4 givenname: Alejandro surname: Bruhn fullname: Bruhn, Alejandro organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 5 givenname: Carlos surname: Romero fullname: Romero, Carlos organization: Unidad de Pacientes Críticos, Hospital Clínico Universidad de Chile, Santos Dumont 999, Santiago, Chile – sequence: 6 givenname: Maximiliano surname: Rovegno fullname: Rovegno, Maximiliano organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 7 givenname: Rodolfo surname: Neira fullname: Neira, Rodolfo organization: Unidad de Pacientes Críticos, Hospital Clínico Universidad de Chile, Santos Dumont 999, Santiago, Chile – sequence: 8 givenname: Sebastian surname: Bravo fullname: Bravo, Sebastian organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 9 givenname: Ricardo surname: Castro fullname: Castro, Ricardo organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 10 givenname: Eduardo surname: Kattan fullname: Kattan, Eduardo organization: Departamento de Medicina Intensiva, Pontificia Universidad Católica de Chile, Marcoleta 367, Santiago, Chile – sequence: 11 givenname: Can surname: Ince fullname: Ince, Can organization: Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands |
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| Cites_doi | 10.1056/NEJMoa010307 10.1007/s00134-007-0531-4 10.1186/cc5144 10.1186/cc2894 10.1186/cc8011 10.1097/MCC.0b013e32832b70e5 10.1097/00003246-199206000-00025 10.1097/CCM.0b013e31819869db 10.1016/j.resuscitation.2005.01.009 10.1007/s00134-008-1007-x 10.1007/s00134-007-0680-5 10.1097/01.ta.0000202062.49814.f4 10.1097/SHK.0b013e3181971d47 10.1097/01.CCM.0000050454.01978.3B 10.1016/j.ajem.2007.06.026 10.1016/S0002-9610(97)89552-9 10.1007/s00134-006-0118-5 10.1007/s00134-010-1970-x 10.1007/s00134-008-1199-0 10.1007/s00134-005-2790-2 10.1007/s00134-007-0934-2 10.1186/cc7802 10.1097/00005373-200104000-00005 10.1161/01.CIR.39.1.131 10.1016/S0140-6736(05)71045-X |
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| Keywords | Septic shock Peripheral perfusion Lactate Resuscitation |
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| References | Lima, Bakker (bb0095) 2005; 31 Kaplan, McPartland, Santora, Trooskin (bb0055) 2001; 50 Lima, van Bommel, Jansen, Ince, Bakker (bb0130) 2009; 13 Bracht, Hänggi, Jeker, Wegmüller, Porta, Tüller (bb0035) 2007; 11 Dellinger, Levy, Carlet, Bion, Parker, Jaeschke (bb0010) 2008; 34 Vallée, Vallet, Mathe, Parraguette, Mari, Silva (bb0030) 2008; 34 Anderson, Kelly, Kerr, Clooney, Jolley (bb0105) 2008; 26 Rivers, Nguyen, Havstad, Ressler, Muzzin, Knoblich (bb0020) 2001; 345 Lima, Jansen, van Bommel, Ince, Bakker (bb0060) 2009; 37 Hernandez, Peña, Cornejo, Rovegno, Retamal, Navarro (bb0025) 2009; 13 Hernandez, Bruhn, Romero, Larrondo, De La Fuente, Cornejo (bb0075) 2006; 60 Spronk, Zandstra, Ince (bb0040) 2004; 8 Levy, Gibot, Franck, Cravoisy, Bollaert (bb0100) 2005; 365 Joly, Weil (bb0050) 1969; 39 Arnold, Shapiro, Jones, Schorr, Pope, Casner (bb0115) 2009; 32 Levy, Fink, Marshall, Abraham, Angus, Cook (bb0065) 2003; 31 Boerma, Ince (bb0125) 2010; 36 Hernandez, Castro, Romero, De la Hoz, Angulo, Aranguiz (bb0135) 2010 Hernandez, Bruhn, Romero, Javier Larrondo, De La Fuente, Castillo (bb0070) 2005; 66 Bakker, Gris, Coffernils, Kahn, Vincent (bb0120) 1996; 171 Sevransky (bb0110) 2009; 15 (bb0005) 1992; 20 Cornejo, Downey, Castro, Romero, Regueira, Vega (bb0080) 2006; 32 Howell, Donnino, Clardy, Talmor, Shapiro (bb0045) 2007; 33 Antonelli, Levy, Andrews, Chastre, Hudson, Manthous (bb0015) 2007; 33 Castro, Regueira, Aguirre, Llanos, Bruhn, Bugedo (bb0085) 2008; 74 Boerma, Kuiper, Kingma, Egbers, Gerritsen, Ince (bb0090) 2008; 34 Boerma (10.1016/j.jcrc.2011.05.024_bb0090) 2008; 34 Howell (10.1016/j.jcrc.2011.05.024_bb0045) 2007; 33 Kaplan (10.1016/j.jcrc.2011.05.024_bb0055) 2001; 50 Levy (10.1016/j.jcrc.2011.05.024_bb0065) 2003; 31 Dellinger (10.1016/j.jcrc.2011.05.024_bb0010) 2008; 34 Sevransky (10.1016/j.jcrc.2011.05.024_bb0110) 2009; 15 (10.1016/j.jcrc.2011.05.024_bb0005) 1992; 20 Anderson (10.1016/j.jcrc.2011.05.024_bb0105) 2008; 26 Bakker (10.1016/j.jcrc.2011.05.024_bb0120) 1996; 171 Spronk (10.1016/j.jcrc.2011.05.024_bb0040) 2004; 8 Joly (10.1016/j.jcrc.2011.05.024_bb0050) 1969; 39 Lima (10.1016/j.jcrc.2011.05.024_bb0130) 2009; 13 Lima (10.1016/j.jcrc.2011.05.024_bb0060) 2009; 37 Hernandez (10.1016/j.jcrc.2011.05.024_bb0135) 2010 Arnold (10.1016/j.jcrc.2011.05.024_bb0115) 2009; 32 Castro (10.1016/j.jcrc.2011.05.024_bb0085) 2008; 74 Boerma (10.1016/j.jcrc.2011.05.024_bb0125) 2010; 36 Bracht (10.1016/j.jcrc.2011.05.024_bb0035) 2007; 11 Rivers (10.1016/j.jcrc.2011.05.024_bb0020) 2001; 345 Antonelli (10.1016/j.jcrc.2011.05.024_bb0015) 2007; 33 Lima (10.1016/j.jcrc.2011.05.024_bb0095) 2005; 31 Levy (10.1016/j.jcrc.2011.05.024_bb0100) 2005; 365 Hernandez (10.1016/j.jcrc.2011.05.024_bb0025) 2009; 13 Hernandez (10.1016/j.jcrc.2011.05.024_bb0075) 2006; 60 Vallée (10.1016/j.jcrc.2011.05.024_bb0030) 2008; 34 Cornejo (10.1016/j.jcrc.2011.05.024_bb0080) 2006; 32 Hernandez (10.1016/j.jcrc.2011.05.024_bb0070) 2005; 66 |
| References_xml | – volume: 11 start-page: R2 year: 2007 ident: bb0035 article-title: Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study publication-title: Crit Care – volume: 32 start-page: 713 year: 2006 end-page: 722 ident: bb0080 article-title: High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock publication-title: Intensive Care Med – volume: 66 start-page: 63 year: 2005 end-page: 69 ident: bb0070 article-title: Management of septic shock with a norepinephrine-based haemodynamic algorithm publication-title: Resuscitation – volume: 13 start-page: S13 year: 2009 ident: bb0130 article-title: Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients publication-title: Crit Care – volume: 34 start-page: 1294 year: 2008 end-page: 1298 ident: bb0090 article-title: Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study publication-title: Intensive Care Med – volume: 26 start-page: 62 year: 2008 end-page: 65 ident: bb0105 article-title: Impact of patient and environmental factors on capillary refill time in adults publication-title: Am J Emerg Med – volume: 31 start-page: 1316 year: 2005 end-page: 1326 ident: bb0095 article-title: Noninvasive monitoring of peripheral perfusion publication-title: Intensive Care Med – year: 2010 ident: bb0135 article-title: Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? publication-title: J Crit Care – volume: 33 start-page: 575 year: 2007 end-page: 590 ident: bb0015 article-title: Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006 publication-title: Intensive Care Med – volume: 345 start-page: 1368 year: 2001 end-page: 1377 ident: bb0020 article-title: Early goal-directed therapy in the treatment of severe sepsis and septic shock publication-title: N Engl J Med – volume: 365 start-page: 871 year: 2005 end-page: 875 ident: bb0100 article-title: Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study publication-title: Lancet – volume: 13 start-page: R63 year: 2009 ident: bb0025 article-title: Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study publication-title: Crit Care – volume: 39 start-page: 131 year: 1969 end-page: 138 ident: bb0050 article-title: Temperature of the great toe as an indication of the severity of shock publication-title: Circulation – volume: 33 start-page: 1892 year: 2007 end-page: 1899 ident: bb0045 article-title: Occult hypoperfusion and mortality in patients with suspected infection publication-title: Intensive Care Med – volume: 15 start-page: 234 year: 2009 end-page: 238 ident: bb0110 article-title: Clinical assessment of hemodynamically unstable patients publication-title: Curr Opin Crit Care – volume: 171 start-page: 221 year: 1996 end-page: 226 ident: bb0120 article-title: Serial blood lactate levels can predict the development of multiple organ failure following septic shock publication-title: Am J Surg – volume: 50 start-page: 620 year: 2001 end-page: 627 ident: bb0055 article-title: Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients publication-title: J Trauma – volume: 34 start-page: 17 year: 2008 end-page: 60 ident: bb0010 article-title: Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 publication-title: Intensive Care Med – volume: 34 start-page: 2218 year: 2008 end-page: 2225 ident: bb0030 article-title: Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? publication-title: Intensive Care Med – volume: 60 start-page: 77 year: 2006 end-page: 81 ident: bb0075 article-title: Implementation of a norepinephrine-based protocol for management of septic shock: a pilot feasibility study publication-title: J Trauma – volume: 37 start-page: 934 year: 2009 end-page: 938 ident: bb0060 article-title: The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients publication-title: Crit Care Med – volume: 20 start-page: 864 year: 1992 end-page: 874 ident: bb0005 article-title: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis publication-title: Crit Care Med – volume: 32 start-page: 35 year: 2009 end-page: 39 ident: bb0115 article-title: Multi-center study of early lactate clearance as a determinant of survival in patients with presumed sepsis publication-title: Shock – volume: 8 start-page: 462 year: 2004 end-page: 468 ident: bb0040 article-title: Bench-to-bedside review: sepsis is a disease of the microcirculation publication-title: Crit Care – volume: 31 start-page: 1250 year: 2003 end-page: 1256 ident: bb0065 article-title: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference publication-title: Crit Care Med. – volume: 36 start-page: 2004 year: 2010 end-page: 2018 ident: bb0125 article-title: The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients publication-title: Intensive Care Med – volume: 74 start-page: 223 year: 2008 end-page: 231 ident: bb0085 article-title: An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock publication-title: Minerva Anestesiol – volume: 345 start-page: 1368 year: 2001 ident: 10.1016/j.jcrc.2011.05.024_bb0020 article-title: Early goal-directed therapy in the treatment of severe sepsis and septic shock publication-title: N Engl J Med doi: 10.1056/NEJMoa010307 – volume: 33 start-page: 575 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0015 article-title: Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006 publication-title: Intensive Care Med doi: 10.1007/s00134-007-0531-4 – volume: 11 start-page: R2 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0035 article-title: Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study publication-title: Crit Care doi: 10.1186/cc5144 – volume: 8 start-page: 462 year: 2004 ident: 10.1016/j.jcrc.2011.05.024_bb0040 article-title: Bench-to-bedside review: sepsis is a disease of the microcirculation publication-title: Crit Care doi: 10.1186/cc2894 – volume: 13 start-page: S13 issue: Suppl 5 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0130 article-title: Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients publication-title: Crit Care doi: 10.1186/cc8011 – volume: 15 start-page: 234 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0110 article-title: Clinical assessment of hemodynamically unstable patients publication-title: Curr Opin Crit Care doi: 10.1097/MCC.0b013e32832b70e5 – volume: 20 start-page: 864 year: 1992 ident: 10.1016/j.jcrc.2011.05.024_bb0005 article-title: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis publication-title: Crit Care Med doi: 10.1097/00003246-199206000-00025 – volume: 37 start-page: 934 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0060 article-title: The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients publication-title: Crit Care Med doi: 10.1097/CCM.0b013e31819869db – volume: 66 start-page: 63 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0070 article-title: Management of septic shock with a norepinephrine-based haemodynamic algorithm publication-title: Resuscitation doi: 10.1016/j.resuscitation.2005.01.009 – volume: 34 start-page: 1294 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0090 article-title: Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study publication-title: Intensive Care Med doi: 10.1007/s00134-008-1007-x – volume: 33 start-page: 1892 year: 2007 ident: 10.1016/j.jcrc.2011.05.024_bb0045 article-title: Occult hypoperfusion and mortality in patients with suspected infection publication-title: Intensive Care Med doi: 10.1007/s00134-007-0680-5 – volume: 60 start-page: 77 year: 2006 ident: 10.1016/j.jcrc.2011.05.024_bb0075 article-title: Implementation of a norepinephrine-based protocol for management of septic shock: a pilot feasibility study publication-title: J Trauma doi: 10.1097/01.ta.0000202062.49814.f4 – volume: 32 start-page: 35 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0115 article-title: Multi-center study of early lactate clearance as a determinant of survival in patients with presumed sepsis publication-title: Shock doi: 10.1097/SHK.0b013e3181971d47 – year: 2010 ident: 10.1016/j.jcrc.2011.05.024_bb0135 article-title: Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? publication-title: J Crit Care – volume: 31 start-page: 1250 year: 2003 ident: 10.1016/j.jcrc.2011.05.024_bb0065 article-title: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference publication-title: Crit Care Med. doi: 10.1097/01.CCM.0000050454.01978.3B – volume: 26 start-page: 62 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0105 article-title: Impact of patient and environmental factors on capillary refill time in adults publication-title: Am J Emerg Med doi: 10.1016/j.ajem.2007.06.026 – volume: 171 start-page: 221 year: 1996 ident: 10.1016/j.jcrc.2011.05.024_bb0120 article-title: Serial blood lactate levels can predict the development of multiple organ failure following septic shock publication-title: Am J Surg doi: 10.1016/S0002-9610(97)89552-9 – volume: 32 start-page: 713 year: 2006 ident: 10.1016/j.jcrc.2011.05.024_bb0080 article-title: High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock publication-title: Intensive Care Med doi: 10.1007/s00134-006-0118-5 – volume: 74 start-page: 223 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0085 article-title: An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock publication-title: Minerva Anestesiol – volume: 36 start-page: 2004 year: 2010 ident: 10.1016/j.jcrc.2011.05.024_bb0125 article-title: The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients publication-title: Intensive Care Med doi: 10.1007/s00134-010-1970-x – volume: 34 start-page: 2218 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0030 article-title: Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? publication-title: Intensive Care Med doi: 10.1007/s00134-008-1199-0 – volume: 31 start-page: 1316 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0095 article-title: Noninvasive monitoring of peripheral perfusion publication-title: Intensive Care Med doi: 10.1007/s00134-005-2790-2 – volume: 34 start-page: 17 year: 2008 ident: 10.1016/j.jcrc.2011.05.024_bb0010 article-title: Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 publication-title: Intensive Care Med doi: 10.1007/s00134-007-0934-2 – volume: 13 start-page: R63 year: 2009 ident: 10.1016/j.jcrc.2011.05.024_bb0025 article-title: Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study publication-title: Crit Care doi: 10.1186/cc7802 – volume: 50 start-page: 620 year: 2001 ident: 10.1016/j.jcrc.2011.05.024_bb0055 article-title: Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients publication-title: J Trauma doi: 10.1097/00005373-200104000-00005 – volume: 39 start-page: 131 year: 1969 ident: 10.1016/j.jcrc.2011.05.024_bb0050 article-title: Temperature of the great toe as an indication of the severity of shock publication-title: Circulation doi: 10.1161/01.CIR.39.1.131 – volume: 365 start-page: 871 year: 2005 ident: 10.1016/j.jcrc.2011.05.024_bb0100 article-title: Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study publication-title: Lancet doi: 10.1016/S0140-6736(05)71045-X |
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| Snippet | Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and central-to-toe... Abstract Purpose Perfusion assessment during septic shock resuscitation is difficult and usually complex determinations. Capillary refill time (CRT) and... |
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| SubjectTerms | Aged Catheters Chile Critical Care Extremities - blood supply Female Fluid Therapy Heart rate Humans Lactate Lactic Acid - blood Male Microcirculation Middle Aged Monitoring, Physiologic - methods Multivariate Analysis Peripheral perfusion Prospective Studies Regional Blood Flow Resuscitation Sepsis Septic shock Shock, Septic - physiopathology Shock, Septic - therapy Skin Temperature Studies Toes - blood supply Veins & arteries |
| Title | Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study |
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