Neuromodulatory Correlates of Pupil Dilation

Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are thought to coincide with the activity of neuromodulators, including noradrenaline and acetylcholine, producing alterations in the brain state and corresponding changes in behavior. Here we review mechanisms un...

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Veröffentlicht in:Frontiers in neural circuits Jg. 12; S. 21
Hauptverfasser: Larsen, Rylan S., Waters, Jack
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Switzerland Frontiers Research Foundation 09.03.2018
Frontiers Media S.A
Schlagworte:
Acetylcholine
Animal cognition
Animals
Behavior
Cortex
Humans
Light
Neocortex - metabolism
Nervous system
Neuromodulation
Neurons
Neurons - metabolism
Neuroscience
noradrenaline
Norepinephrine
Organ Size
Pupil - physiology
pupillometry
Retina
neuromodulation
norepinephrine
pupillometry
noradrenaline
acetylcholine
ISSN:1662-5110, 1662-5110
Online-Zugang:Volltext
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Zusammenfassung:Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are thought to coincide with the activity of neuromodulators, including noradrenaline and acetylcholine, producing alterations in the brain state and corresponding changes in behavior. Here we review mechanisms underlying the control of pupil diameter and how these mechanisms are correlated with changes in cortical activity and the recruitment of neuromodulatory circuits.
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ObjectType-Feature-2
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Reviewed by: Tobias H. Donner, Universitätsklinikum Hamburg-Eppendorf, Germany; Paula Louise Croxson, Icahn School of Medicine at Mount Sinai, United States
Edited by: Anita Disney, Vanderbilt University, United States
ISSN:1662-5110
1662-5110
DOI:10.3389/fncir.2018.00021