Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity

The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to antigens and commensals, and a tissue susceptible to one of the most prevalent human inflammatory diseases, periodontitis. To aid in understanding tissue-specific pathophysiology, we compile a single-cell tran...

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Veröffentlicht in:	Cell Jg. 184; H. 15; S. 4090
Hauptverfasser:	Williams, Drake Winslow, Greenwell-Wild, Teresa, Brenchley, Laurie, Dutzan, Nicolas, Overmiller, Andrew, Sawaya, Andrew Phillip, Webb, Simone, Martin, Daniel, Hajishengallis, George, Divaris, Kimon, Morasso, Maria, Haniffa, Muzlifah, Moutsopoulos, Niki Maria
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 22.07.2021
Schlagworte:	Adult Epithelial Cells - cytology Gene Expression Regulation Genetic Predisposition to Disease Gingiva - pathology Humans Immunity, Mucosal Inflammation - immunology Inflammation - pathology Microbiota Mouth Mucosa - cytology Mouth Mucosa - immunology Myeloid Cells - cytology Neutrophils - cytology Periodontitis - genetics Periodontitis - immunology Periodontitis - pathology Single-Cell Analysis Stromal Cells - cytology T-Lymphocytes - cytology stromal -immune interaction oral mucosal immunity human oral mucosal single-cell atlas oral atlas periodontitis single-cell atlas mucosal immunity
ISSN:	1097-4172, 1097-4172
Online-Zugang:	Weitere Angaben
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