Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

The effectiveness of SARS-CoV-2 vaccines and therapeutic antibodies have been limited by the continuous emergence of viral variants and by the restricted diffusion of antibodies from circulation into the sites of respiratory virus infection. Here, we report the identification of two highly conserved...

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Bibliographic Details
Published in:	Cell Vol. 185; no. 8; p. 1389
Main Authors:	Li, Cheng, Zhan, Wuqiang, Yang, Zhenlin, Tu, Chao, Hu, Gaowei, Zhang, Xiang, Song, Wenping, Du, Shujuan, Zhu, Yuanfei, Huang, Keke, Kong, Yu, Zhang, Meng, Mao, Qiyu, Gu, Xiaodan, Zhang, Yi, Xie, Youhua, Deng, Qiang, Song, Yuanlin, Chen, Zhenguo, Lu, Lu, Jiang, Shibo, Wu, Yanling, Sun, Lei, Ying, Tianlei
Format:	Journal Article
Language:	English
Published:	United States 14.04.2022
Subjects:	Administration, Inhalation Animals Antibodies, Neutralizing Antibodies, Viral COVID-19 COVID-19 Vaccines - administration & dosage Disease Models, Animal Humans Mice SARS-CoV-2 Single-Domain Antibodies Spike Glycoprotein, Coronavirus - chemistry bispecific antibody inhalation SARS-CoV-2 broad neutralization single-domain antibody
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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