Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

The effectiveness of SARS-CoV-2 vaccines and therapeutic antibodies have been limited by the continuous emergence of viral variants and by the restricted diffusion of antibodies from circulation into the sites of respiratory virus infection. Here, we report the identification of two highly conserved...

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Veröffentlicht in:	Cell Jg. 185; H. 8; S. 1389
Hauptverfasser:	Li, Cheng, Zhan, Wuqiang, Yang, Zhenlin, Tu, Chao, Hu, Gaowei, Zhang, Xiang, Song, Wenping, Du, Shujuan, Zhu, Yuanfei, Huang, Keke, Kong, Yu, Zhang, Meng, Mao, Qiyu, Gu, Xiaodan, Zhang, Yi, Xie, Youhua, Deng, Qiang, Song, Yuanlin, Chen, Zhenguo, Lu, Lu, Jiang, Shibo, Wu, Yanling, Sun, Lei, Ying, Tianlei
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 14.04.2022
Schlagworte:	Administration, Inhalation Animals Antibodies, Neutralizing Antibodies, Viral COVID-19 COVID-19 Vaccines - administration & dosage Disease Models, Animal Humans Mice SARS-CoV-2 Single-Domain Antibodies Spike Glycoprotein, Coronavirus - chemistry bispecific antibody inhalation SARS-CoV-2 broad neutralization single-domain antibody
ISSN:	1097-4172, 1097-4172
Online-Zugang:	Weitere Angaben
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