BWM: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design

Sparse energy functions that ignore long range interactions between residue pairs are frequently used by protein design algorithms to reduce computational cost. Current dynamic programming algorithms that fully exploit the optimal substructure produced by these energy functions only compute the GMEC...

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Vydané v:	Journal of computational biology Ročník 23; číslo 6; s. 413
Hlavní autori:	Jou, Jonathan D, Jain, Swati, Georgiev, Ivelin S, Donald, Bruce R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.06.2016
Predmet:	Algorithms Amino Acid Sequence Computational Biology - methods Models, Molecular Protein Conformation Proteins - chemistry Software sparse residue interaction graphs ensemble-based algorithms dynamic programming provable algorithms OSPREY branch-decomposition protein design
ISSN:	1557-8666, 1557-8666
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