BWM: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design

Sparse energy functions that ignore long range interactions between residue pairs are frequently used by protein design algorithms to reduce computational cost. Current dynamic programming algorithms that fully exploit the optimal substructure produced by these energy functions only compute the GMEC...

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Bibliographic Details

Published in:	Journal of computational biology Vol. 23; no. 6; p. 413
Main Authors:	Jou, Jonathan D, Jain, Swati, Georgiev, Ivelin S, Donald, Bruce R
Format:	Journal Article
Language:	English
Published:	United States 01.06.2016
Subjects:	Algorithms Amino Acid Sequence Computational Biology - methods Models, Molecular Protein Conformation Proteins - chemistry Software sparse residue interaction graphs ensemble-based algorithms dynamic programming provable algorithms OSPREY branch-decomposition protein design
ISSN:	1557-8666, 1557-8666
Online Access:	Get more information
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