Electrochemical biosensors for pathogen detection

Recent advances in electrochemical biosensors for pathogen detection are reviewed. Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and biosensor performance. Transduction elements are discu...

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Vydáno v:	Biosensors & bioelectronics Ročník 159; s. 112214
Hlavní autoři:	Cesewski, Ellen, Johnson, Blake N.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier B.V 01.07.2020
Témata:	Animals antibodies Bacteria - isolation & purification Betacoronavirus - isolation & purification Bio-threat Biosensing Techniques - instrumentation Biosensors Coronavirus Infections - diagnosis Coronavirus Infections - virology COVID-19 diagnostic techniques Electrochemical Electrochemical Techniques electrochemistry Electrodes environmental monitoring Eukaryota - isolation & purification food pathogens Food safety Humans Medical diagnostics microbial detection Microbiological Techniques - instrumentation Microbiological Techniques - standards Microbiological Techniques - trends oligonucleotides Pandemics Pathogen quantification plant pathogens Pneumonia, Viral - diagnosis Pneumonia, Viral - virology polymers process monitoring SARS-CoV-2 Virus detection Viruses - isolation & purification Water safety COVID-19 Bio-threat Water safety Medical diagnostics Pathogen quantification Food safety Virus detection Biosensors Electrochemical
ISSN:	0956-5663, 1873-4235, 1873-4235
On-line přístup:	Získat plný text
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Shrnutí:	Recent advances in electrochemical biosensors for pathogen detection are reviewed. Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and biosensor performance. Transduction elements are discussed in terms of electrode material and form factor. Biorecognition elements for pathogen detection, including antibodies, aptamers, and imprinted polymers, are discussed in terms of availability, production, and immobilization approach. Emerging areas of electrochemical biosensor design are reviewed, including electrode modification and transducer integration. Measurement formats for pathogen detection are classified in terms of sample preparation and secondary binding steps. Applications of electrochemical biosensors for the detection of pathogens in food and water safety, medical diagnostics, environmental monitoring, and bio-threat applications are highlighted. Future directions and challenges of electrochemical biosensors for pathogen detection are discussed, including wearable and conformal biosensors, detection of plant pathogens, multiplexed detection, reusable biosensors for process monitoring applications, and low-cost, disposable biosensors. •Comprehensive review of electrochemical biosensor-based pathogen detection.•Review of emerging electrodes for transduction of pathogen binding via electrochemical methods.•Discussion of emerging electrochemical biosensor designs, including flexible and wearable form factors.•Highlight of electrochemical biosensors for coronavirus detection.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	0956-5663 1873-4235 1873-4235
DOI:	10.1016/j.bios.2020.112214