Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses

How immune dysregulation affects recovery from COVID-19 infection in patients with cancer remains unclear. We analyzed cellular and humoral immune responses in 103 patients with prior COVID-19 infection, more than 20% of whom had delayed viral clearance. Delayed clearance was associated with loss of...

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Vydané v:	Cancer cell Ročník 40; číslo 7; s. 738
Hlavní autori:	Lyudovyk, Olga, Kim, Justin Y, Qualls, David, Hwee, Madeline A, Lin, Ya-Hui, Boutemine, Sawsan R, Elhanati, Yuval, Solovyov, Alexander, Douglas, Melanie, Chen, Eunise, Babady, N Esther, Ramanathan, Lakshmi, Vedantam, Pallavi, Bandlamudi, Chaitanya, Gouma, Sigrid, Wong, Philip, Hensley, Scott E, Greenbaum, Benjamin, Huang, Alexander C, Vardhana, Santosha A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 11.07.2022
Predmet:	CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes COVID-19 Humans Immunity, Cellular Immunity, Humoral Immunologic Memory Receptors, Antigen, T-Cell SARS-CoV-2 CD20 COVID-19 convalescent SARS-CoV-2 T cell cancer rituximab
ISSN:	1878-3686, 1878-3686
On-line prístup:	Zistit podrobnosti o prístupe
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