Impact of preoperative chemotherapy as initial treatment for advanced gastric cancer with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) or localized peritoneal metastasis (P1a): a multi-institutional retrospective study
Background Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monot...
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| Vydané v: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association Ročník 24; číslo 3; s. 701 - 709 |
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| Hlavní autori: | , , , , , , , , , , , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Singapore
Springer Singapore
01.05.2021
Springer Nature B.V |
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| ISSN: | 1436-3291, 1436-3305, 1436-3305 |
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| Abstract | Background
Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a.
Methods
We retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment.
Results
A total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others (
n
= 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87–1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85–1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group.
Conclusions
Although, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0. |
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| AbstractList | Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a.
We retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment.
A total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others (n = 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87-1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85-1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group.
Although, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0. Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a.BACKGROUNDGastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a.We retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment.METHODSWe retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment.A total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others (n = 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87-1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85-1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group.RESULTSA total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others (n = 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87-1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85-1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group.Although, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0.CONCLUSIONSAlthough, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0. BackgroundGastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a.MethodsWe retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment.ResultsA total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others (n = 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87–1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85–1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group.ConclusionsAlthough, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0. Background Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) and/or localized peritoneal metastasis (P1a), gastrectomy followed by S1 monotherapy is one of the most widely accepted therapeutic strategy in Japan. This study investigated the efficacy of preoperative chemotherapy as initial treatment in GC patients with CY1 and/or P1a. Methods We retrospectively reviewed GC patients diagnosed with CY1 and/or P1a at 34 institutions in Japan between 2008 and 2012. Selection criteria were: adenocarcinoma, no distant metastasis except CY1 or P1a, and no prior treatment. The subjects were divided into an Initial-Chemotherapy group and an Initial-Surgery group, according to the initial treatment. Results A total of 824 patients were collected and 713 eligible patients were identified for this study. As the initial treatment, 150 patients received chemotherapy (Initial-Cx), and 563 patients underwent surgery (Initial-Sx). Initial-Cx regimens were cisplatin plus S1/docetaxel plus cisplatin plus S1/others ( n = 90/37/23). Both overall survival (OS) and progression-free survival (PFS) were similar between the Initial-Cx and Initial-Sx groups (median OS 24.8 and 24.0 months, HR 1.07, 95% CI 0.87–1.3; median PFS 14.9 and 13.9 months, HR 1.04, 95% CI 0.85–1.27). The 5-year OS rates were 22.3% in the Initial-Cx group and 21.5% in the Initial-Sx group. Conclusions Although, the preoperative chemotherapy did not show a survival benefit for GC patients with CY1 and/or P1a, initial-Cx showed favorable survival in patients who converted to P0 and CY0. |
| Author | Matsushita, Hisayuki Hosoda, Kei Kinoshita, Takahiro Yamada, Tatsuya Satoh, Taroh Yamaguchi, Toshifumi Fukagawa, Takeo Terashima, Masanori Tanaka, Ryo Kakihara, Naoki Nishikawa, Kazuhiro Katai, Hitoshi Boku, Narikazu Aizawa, Masaki Nagashima, Kengo Ohashi, Manabu Haruta, Shusuke Takashima, Atsuo Ishiyama, Koshiro Yunome, Gen Yuasa, Yasuhiro |
| Author_xml | – sequence: 1 givenname: Toshifumi surname: Yamaguchi fullname: Yamaguchi, Toshifumi organization: Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital – sequence: 2 givenname: Atsuo orcidid: 0000-0002-8456-1248 surname: Takashima fullname: Takashima, Atsuo email: atakashi@ncc.go.jp organization: Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital – sequence: 3 givenname: Kengo surname: Nagashima fullname: Nagashima, Kengo organization: Research Center for Medical and Health Data Science, The Institute of Statistical Mathematics – sequence: 4 givenname: Masanori surname: Terashima fullname: Terashima, Masanori organization: Division of Gastric Surgery, Shizuoka Cancer Center – sequence: 5 givenname: Masaki surname: Aizawa fullname: Aizawa, Masaki organization: Department of Gastroenterological Surgery, Niigata Cancer Center Hospital – sequence: 6 givenname: Manabu surname: Ohashi fullname: Ohashi, Manabu organization: Department of Gastroenterological Surgery, Cancer Institute Hospital – sequence: 7 givenname: Ryo surname: Tanaka fullname: Tanaka, Ryo organization: Department of General and Gastroenterological Surgery, Osaka Medical College Hospital – sequence: 8 givenname: Tatsuya surname: Yamada fullname: Yamada, Tatsuya organization: Department of Gastroenterological Surgery, Saitama Cancer Center – sequence: 9 givenname: Takahiro surname: Kinoshita fullname: Kinoshita, Takahiro organization: Gastric Surgery Division, National Cancer Center Hospital East – sequence: 10 givenname: Hisayuki surname: Matsushita fullname: Matsushita, Hisayuki organization: Department of Surgery, Tochigi Cancer Center – sequence: 11 givenname: Koshiro surname: Ishiyama fullname: Ishiyama, Koshiro organization: Department of Surgery, Yamagata Prefectural Central Hospital – sequence: 12 givenname: Kei surname: Hosoda fullname: Hosoda, Kei organization: Department of Upper Gastrointestinal Surgery, Kitasato University School of Medicine – sequence: 13 givenname: Yasuhiro surname: Yuasa fullname: Yuasa, Yasuhiro organization: Department of Gastroenterological Surgery, Tokushima Red Cross Hospital – sequence: 14 givenname: Shusuke surname: Haruta fullname: Haruta, Shusuke organization: Department of Gastroenterological Surgery, Toranomon Hospital – sequence: 15 givenname: Naoki surname: Kakihara fullname: Kakihara, Naoki organization: Department of Surgery, Japanese Red Cross Kyoto Daini Hospital – sequence: 16 givenname: Kazuhiro surname: Nishikawa fullname: Nishikawa, Kazuhiro organization: Department of Surgery, National Hospital Organization Osaka National Hospital – sequence: 17 givenname: Gen surname: Yunome fullname: Yunome, Gen organization: Department of Surgery, Sendai Medical Center – sequence: 18 givenname: Taroh surname: Satoh fullname: Satoh, Taroh organization: Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine – sequence: 19 givenname: Takeo surname: Fukagawa fullname: Fukagawa, Takeo organization: Department of Surgery, Teikyo University School of Medicine – sequence: 20 givenname: Hitoshi surname: Katai fullname: Katai, Hitoshi organization: Division of Gastric Surgery, National Cancer Center Hospital – sequence: 21 givenname: Narikazu surname: Boku fullname: Boku, Narikazu organization: Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33179192$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1245/s10434-019-07697-x 10.1007/s10120-014-0388-5 10.1245/s10434-009-0706-z 10.1016/S0140-6736(11)61873-4 10.1016/S1470-2045(15)00553-7 10.1007/s10120-011-0066-9 10.1016/j.ejca.2020.02.002 10.1056/NEJMoa072252 10.1016/S1470-2045(08)70035-4 10.1016/j.surg.2015.04.004 10.1245/s10434-019-07229-7 10.1007/s10147-017-1164-4 10.1016/S1470-2045(09)70259-1 10.1016/S1470-2045(15)00410-6 10.1007/s10120-007-0436-5 10.1093/annonc/mdy540 10.1007/s10120-012-0156-3 10.1016/S2468-1253(19)30083-4 10.1007/s10120-018-0817-y 10.1200/JCO.2018.77.8613 10.1093/annonc/mdz183.002 10.1007/s10120-011-0041-5 10.1002/(SICI)1096-9098(199910)72:2<60::AID-JSO3>3.0.CO;2-1 10.1016/S0002-9610(99)00162-2 10.1007/s10120-020-01042-y |
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| References | Okabe, Ueda, Obama, Hosogi, Sakai (CR12) 2009; 16 Hironaka, Sugimoto, Yamaguchi, Moriwaki, Komatsu, Nishina (CR21) 2016; 17 Boku, Ryu, Kato, Chung, Minashi, Lee (CR23) 2019; 30 Yamada, Boku, Mizusawa, Iwasa, Kadowaki, Nakayama (CR19) 2019; 4 Nakayama, Chin, Matsushima, Takahari, Takahari, Ogura, Shinozaki (CR10) 2017; 22 Ishigami, Fujiwara, Fukushima, Nashimoto, Yabusaki, Imano (CR26) 2018; 36 Koizumi, Narahara, Hara (CR17) 2008; 9 Naoto, Mitsuro, Takaki, Takiguchi, Fujitani, Miyamoto (CR25) 2018; 21 Nakajima, Harashima, Hirata, Kajitani (CR3) 1978; 22 Okabe, Hata, Hosogi, Ueda, Ota, Kinjo (CR13) 2019; 26 Satoh, Okabe, Teramukai, Hasegawa, Ozaki, Ueda (CR14) 2012; 15 Fujiwara, Doki, Taniguchi, Sohma, Takiguchi, Miyata (CR2) 2007; 10 Kang, Chin, Chung, Kadowaki, Oh, Nakayama (CR22) 2019; 30 Fujitani, Yang, Mizusawa, Kim, Terashima, Han (CR20) 2016; 17 CR5 Bang, Kim, Yang, Chung, Park, Lee (CR16) 2012; 379 Kodera, Ito, Mochizuki, Ohashi, Tanaka (CR8) 2012; 15 Kodera, Yamamura, Shimizu, Torii, Hirai, Kobayashi (CR7) 1999; 72 Cabalag, Chan, Kaneko, Duong (CR6) 2015; 18 (CR4) 2011; 14 Boku, Yamamoto, Fukuda, Shirao, Doi, Sawaki (CR18) 2009; 10 Kawazoe, Yamaguchi, Yasui, Negoro, Azuma, Amagai (CR24) 2020; 129 Bando, Yonemura, Takeshita, Taniguchi, Yasui, Yoshimitsu (CR1) 1999; 178 Kano, Kosugi, Ishikawa, Otani, Muneoka, Sato (CR9) 2015; 158 Yamaguchi, Takashima, Nagashima, Makuuchi, Aizawa, Ohashi (CR11) 2020; 27 Sakuramoto, Sasako, Yamaguchi, Kinoshita, Fujii, Nashimoto (CR15) 2007; 357 Japanese Gastric Cancer Association (1137_CR4) 2011; 14 T Naoto (1137_CR25) 2018; 21 S Sakuramoto (1137_CR15) 2007; 357 H Okabe (1137_CR12) 2009; 16 T Nakajima (1137_CR3) 1978; 22 Y Fujiwara (1137_CR2) 2007; 10 CS Cabalag (1137_CR6) 2015; 18 1137_CR5 W Koizumi (1137_CR17) 2008; 9 Y Kano (1137_CR9) 2015; 158 S Hironaka (1137_CR21) 2016; 17 S Satoh (1137_CR14) 2012; 15 Y Yamada (1137_CR19) 2019; 4 H Ishigami (1137_CR26) 2018; 36 N Boku (1137_CR23) 2019; 30 E Bando (1137_CR1) 1999; 178 Y Kodera (1137_CR7) 1999; 72 N Boku (1137_CR18) 2009; 10 H Okabe (1137_CR13) 2019; 26 YJ Bang (1137_CR16) 2012; 379 K Fujitani (1137_CR20) 2016; 17 Y Kodera (1137_CR8) 2012; 15 T Yamaguchi (1137_CR11) 2020; 27 I Nakayama (1137_CR10) 2017; 22 Y Kang (1137_CR22) 2019; 30 A Kawazoe (1137_CR24) 2020; 129 |
| References_xml | – volume: 27 start-page: 284 issue: 1 year: 2020 end-page: 292 ident: CR11 article-title: Efficacy of postoperative chemotherapy after resection that leaves no macroscopically visible disease of gastric cancer with positive peritoneal lavage cytology (CY1) or localized peritoneum metastasis (P1a): a multicenter retrospective study publication-title: Ann Surg Oncol doi: 10.1245/s10434-019-07697-x – volume: 18 start-page: 11 issue: 1 year: 2015 end-page: 22 ident: CR6 article-title: A systematic review and meta-analysis of gastric cancer treatment in patients with positive peritoneal cytology publication-title: Gastric Cancer doi: 10.1007/s10120-014-0388-5 – volume: 16 start-page: 3227 issue: 12 year: 2009 end-page: 3236 ident: CR12 article-title: Induction chemotherapy with S-1 plus cisplatin followed by surgery for treatment of gastric cancer with peritoneal dissemination publication-title: Ann Surg Oncol doi: 10.1245/s10434-009-0706-z – volume: 379 start-page: 315 issue: 9813 year: 2012 end-page: 321 ident: CR16 article-title: Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, randomised controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(11)61873-4 – volume: 17 start-page: 309 issue: 3 year: 2016 end-page: 318 ident: CR20 article-title: Gastrectomy plus chemotherapy versus chemotherapy alone for advanced gastric cancer with a single non-curable factor (REGATTA): a phase 3, randomised controlled trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(15)00553-7 – volume: 15 start-page: 61 issue: 1 year: 2012 end-page: 69 ident: CR14 article-title: Phase II trial of combined treatment consisting of preoperative S-1 plus cisplatin followed by gastrectomy and postoperative S-1 for stage IV gastric cancer publication-title: Gastric Cancer doi: 10.1007/s10120-011-0066-9 – volume: 129 start-page: 97 year: 2020 end-page: 106 ident: CR24 article-title: Safety and efficacy of pembrolizumab in combination with S-1 plus oxaliplatin as a first-line treatment in patients with advanced gastric/gastroesophageal junction cancer: Cohort 1 data from the KEYNOTE-659 phase IIb study publication-title: Eur J Cancer doi: 10.1016/j.ejca.2020.02.002 – volume: 357 start-page: 1810 issue: 18 year: 2007 end-page: 1820 ident: CR15 article-title: Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine publication-title: N Engl J Med doi: 10.1056/NEJMoa072252 – volume: 9 start-page: 215 issue: 3 year: 2008 end-page: 221 ident: CR17 article-title: S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(08)70035-4 – volume: 158 start-page: 1581 issue: 6 year: 2015 end-page: 1589 ident: CR9 article-title: Prognostic significance of peritoneal lavage cytology at three cavities in patients with gastric cancer publication-title: Surgery doi: 10.1016/j.surg.2015.04.004 – volume: 26 start-page: 1779 issue: 6 year: 2019 end-page: 1786 ident: CR13 article-title: A phase 2 study of induction chemotherapy using docetaxel, cisplatin, and S1 for gastric cancer with peritoneal metastasis (KUGC06) publication-title: Ann Surg Oncol doi: 10.1245/s10434-019-07229-7 – volume: 22 start-page: 1060 year: 2017 end-page: 1068 ident: CR10 article-title: Retrospective comparison of S-1 plus cisplatin versus S-1 monotherapy for the treatment of advanced gastric cancer patients with positive peritoneal cytology but without gross peritoneal metastasis publication-title: Int J Clin Oncol doi: 10.1007/s10147-017-1164-4 – volume: 10 start-page: 1063 issue: 11 year: 2009 end-page: 1069 ident: CR18 article-title: Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study publication-title: Lancet Oncol. doi: 10.1016/S1470-2045(09)70259-1 – volume: 17 start-page: 99 issue: 1 year: 2016 end-page: 108 ident: CR21 article-title: S-1 plus leucovorin versus S-1 plus leucovorin and oxaliplatin versus S-1 plus cisplatin in patients with advanced gastric cancer: a randomised, multicentre, open-label, phase 2 trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(15)00410-6 – volume: 10 start-page: 197 year: 2007 end-page: 204 ident: CR2 article-title: Genetic detection of free cancer cells in the peritoneal cavity of the patient with gastric cancer: present status and future perspectives publication-title: Gastric Cancer doi: 10.1007/s10120-007-0436-5 – volume: 30 start-page: 250 issue: 2 year: 2019 end-page: 258 ident: CR23 article-title: Safety and efficacy of nivolumab in combination with S-1/capecitabine plus oxaliplatin in patients with previously untreated, unresectable, advanced, or recurrent gastric/gastroesophageal junction cancer: interim results of a randomized, phase II trial (ATTRACTION-4) publication-title: Ann Oncol doi: 10.1093/annonc/mdy540 – volume: 15 start-page: 335 issue: 3 year: 2012 end-page: 337 ident: CR8 article-title: Long-term follow up of patients who were positive for peritoneal lavage cytology:final report from the CCOG0301 study publication-title: Gastric Cancer doi: 10.1007/s10120-012-0156-3 – volume: 4 start-page: 501 issue: 7 year: 2019 end-page: 510 ident: CR19 article-title: Docetaxel plus cisplatin and S-1 versus cisplatin and S-1 in patients with advanced gastric cancer (JCOG1013): an open-label, phase 3, randomised controlled trial publication-title: Lancet Gastroenterol Hepatol doi: 10.1016/S2468-1253(19)30083-4 – volume: 21 start-page: 1014 year: 2018 end-page: 1023 ident: CR25 article-title: A randomized phase II multicenter trial to explore efficacy of weekly intraperitoneal in comparison with intravenous paclitaxel administered immediately after gastrectomy to the patients with high risk of peritoneal recurrence: final results of the INPACT trial publication-title: Gastric Cancer doi: 10.1007/s10120-018-0817-y – volume: 36 start-page: 1922 issue: 19 year: 2018 end-page: 1929 ident: CR26 article-title: Phase III trial comparing intraperitoneal and intravenous paclitaxel plus S-1 versus cisplatin plus S-1 in patients with gastric cancer with peritoneal metastasis: PHOENIX-GC trial publication-title: J Clin Oncol doi: 10.1200/JCO.2018.77.8613 – ident: CR5 – volume: 30 start-page: iv 153 issue: Suppl 4 year: 2019 ident: CR22 article-title: A phase III study of TAS-118 plus oxaliplatin versus S-1 plus cisplatin as first-line chemotherapy in patients with advanced gastric cancer (SOLAR study) publication-title: Ann Oncol. doi: 10.1093/annonc/mdz183.002 – volume: 14 start-page: 101 year: 2011 end-page: 112 ident: CR4 article-title: Japanese classification of gastric carcinoma, 3rd English edition publication-title: Gastric Cancer doi: 10.1007/s10120-011-0041-5 – volume: 72 start-page: 60 year: 1999 end-page: 65 ident: CR7 article-title: Peritoneal washing cytology: prognostic value of positive findings in patients with gastric carcinoma undergoing a potentially curative resection publication-title: J Surg Oncol doi: 10.1002/(SICI)1096-9098(199910)72:2<60::AID-JSO3>3.0.CO;2-1 – volume: 178 start-page: 256 year: 1999 end-page: 262 ident: CR1 article-title: Intraoperative lavage for cytological examination in 1297 patients with gastric carcinoma publication-title: Am J Surg doi: 10.1016/S0002-9610(99)00162-2 – volume: 22 start-page: 225 year: 1978 end-page: 229 ident: CR3 article-title: Prognostic and therapeutic values of peritoneal cytology in gastric cancer publication-title: Acta Cytol – volume: 16 start-page: 3227 issue: 12 year: 2009 ident: 1137_CR12 publication-title: Ann Surg Oncol doi: 10.1245/s10434-009-0706-z – volume: 14 start-page: 101 year: 2011 ident: 1137_CR4 publication-title: Gastric Cancer doi: 10.1007/s10120-011-0041-5 – volume: 72 start-page: 60 year: 1999 ident: 1137_CR7 publication-title: J Surg Oncol doi: 10.1002/(SICI)1096-9098(199910)72:2<60::AID-JSO3>3.0.CO;2-1 – volume: 10 start-page: 197 year: 2007 ident: 1137_CR2 publication-title: Gastric Cancer doi: 10.1007/s10120-007-0436-5 – volume: 4 start-page: 501 issue: 7 year: 2019 ident: 1137_CR19 publication-title: Lancet Gastroenterol Hepatol doi: 10.1016/S2468-1253(19)30083-4 – volume: 21 start-page: 1014 year: 2018 ident: 1137_CR25 publication-title: Gastric Cancer doi: 10.1007/s10120-018-0817-y – volume: 26 start-page: 1779 issue: 6 year: 2019 ident: 1137_CR13 publication-title: Ann Surg Oncol doi: 10.1245/s10434-019-07229-7 – volume: 357 start-page: 1810 issue: 18 year: 2007 ident: 1137_CR15 publication-title: N Engl J Med doi: 10.1056/NEJMoa072252 – ident: 1137_CR5 doi: 10.1007/s10120-020-01042-y – volume: 36 start-page: 1922 issue: 19 year: 2018 ident: 1137_CR26 publication-title: J Clin Oncol doi: 10.1200/JCO.2018.77.8613 – volume: 158 start-page: 1581 issue: 6 year: 2015 ident: 1137_CR9 publication-title: Surgery doi: 10.1016/j.surg.2015.04.004 – volume: 17 start-page: 99 issue: 1 year: 2016 ident: 1137_CR21 publication-title: Lancet Oncol doi: 10.1016/S1470-2045(15)00410-6 – volume: 30 start-page: 250 issue: 2 year: 2019 ident: 1137_CR23 publication-title: Ann Oncol doi: 10.1093/annonc/mdy540 – volume: 18 start-page: 11 issue: 1 year: 2015 ident: 1137_CR6 publication-title: Gastric Cancer doi: 10.1007/s10120-014-0388-5 – volume: 178 start-page: 256 year: 1999 ident: 1137_CR1 publication-title: Am J Surg doi: 10.1016/S0002-9610(99)00162-2 – volume: 10 start-page: 1063 issue: 11 year: 2009 ident: 1137_CR18 publication-title: Lancet Oncol. doi: 10.1016/S1470-2045(09)70259-1 – volume: 129 start-page: 97 year: 2020 ident: 1137_CR24 publication-title: Eur J Cancer doi: 10.1016/j.ejca.2020.02.002 – volume: 22 start-page: 225 year: 1978 ident: 1137_CR3 publication-title: Acta Cytol – volume: 15 start-page: 335 issue: 3 year: 2012 ident: 1137_CR8 publication-title: Gastric Cancer doi: 10.1007/s10120-012-0156-3 – volume: 27 start-page: 284 issue: 1 year: 2020 ident: 1137_CR11 publication-title: Ann Surg Oncol doi: 10.1245/s10434-019-07697-x – volume: 30 start-page: iv 153 issue: Suppl 4 year: 2019 ident: 1137_CR22 publication-title: Ann Oncol. doi: 10.1093/annonc/mdz183.002 – volume: 15 start-page: 61 issue: 1 year: 2012 ident: 1137_CR14 publication-title: Gastric Cancer doi: 10.1007/s10120-011-0066-9 – volume: 9 start-page: 215 issue: 3 year: 2008 ident: 1137_CR17 publication-title: Lancet Oncol doi: 10.1016/S1470-2045(08)70035-4 – volume: 379 start-page: 315 issue: 9813 year: 2012 ident: 1137_CR16 publication-title: Lancet doi: 10.1016/S0140-6736(11)61873-4 – volume: 17 start-page: 309 issue: 3 year: 2016 ident: 1137_CR20 publication-title: Lancet Oncol doi: 10.1016/S1470-2045(15)00553-7 – volume: 22 start-page: 1060 year: 2017 ident: 1137_CR10 publication-title: Int J Clin Oncol doi: 10.1007/s10147-017-1164-4 |
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Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal... Gastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal metastasis... BackgroundGastric cancer (GC) patients with peritoneal metastasis are defined as stage IV in the Japanese classification of GC. For patients with peritoneal... |
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| SubjectTerms | Abdominal Surgery Adenocarcinoma Adult Aged Aged, 80 and over Cancer Research Cellular biology Chemotherapy Cisplatin Cytology Female Gastrectomy Gastric cancer Gastroenterology Humans Japan Male Medical Records Medicine Medicine & Public Health Metastases Metastasis Middle Aged Neoadjuvant Therapy Neoplasm Metastasis Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - therapy Oncology Original Article Patients Peritoneal Lavage Peritoneal Neoplasms - mortality Peritoneal Neoplasms - secondary Peritoneal Neoplasms - therapy Peritoneum Retrospective Studies Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stomach Neoplasms - therapy Surgery Surgical Oncology Survival Survival Analysis Treatment Outcome Young Adult |
| Title | Impact of preoperative chemotherapy as initial treatment for advanced gastric cancer with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) or localized peritoneal metastasis (P1a): a multi-institutional retrospective study |
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