Regulation of biomolecular condensates by interfacial protein clusters

Biomolecular condensates are cellular compartments that can form by phase separation in the absence of limiting membranes. Studying the P granules of , we find that condensate dynamics are regulated by protein clusters that adsorb to the condensate interface. Using in vitro reconstitution, live obse...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 373; číslo 6560; s. 1218
Hlavní autori:	Folkmann, Andrew W, Putnam, Andrea, Lee, Chiu Fan, Seydoux, Geraldine
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 10.09.2021
Predmet:	Animals Caenorhabditis elegans - metabolism Caenorhabditis elegans - physiology Caenorhabditis elegans Proteins - metabolism Intrinsically Disordered Proteins - metabolism Oocytes - metabolism Protein-Tyrosine Kinases - metabolism RNA-Binding Proteins - metabolism Zygote - metabolism
ISSN:	1095-9203, 1095-9203
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