Epigenetic patterns in a complete human genome

The completion of a telomere-to-telomere human reference genome, T2T-CHM13, has resolved complex regions of the genome, including repetitive and homologous regions. Here, we present a high-resolution epigenetic study of previously unresolved sequences, representing entire acrocentric chromosome shor...

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Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 376; no. 6588; p. eabj5089
Main Authors:	Gershman, Ariel, Sauria, Michael E G, Guitart, Xavi, Vollger, Mitchell R, Hook, Paul W, Hoyt, Savannah J, Jain, Miten, Shumate, Alaina, Razaghi, Roham, Koren, Sergey, Altemose, Nicolas, Caldas, Gina V, Logsdon, Glennis A, Rhie, Arang, Eichler, Evan E, Schatz, Michael C, O'Neill, Rachel J, Phillippy, Adam M, Miga, Karen H, Timp, Winston
Format:	Journal Article
Language:	English
Published:	United States 01.04.2022
Subjects:	Centromere - genetics Centromere - metabolism CpG Islands Disease - genetics DNA Methylation Epigenesis, Genetic Genetic Loci Genome, Human Genomics - standards Humans Reference Standards Sequence Analysis, DNA
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
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