Structure, Immunoreactivity, and In Silico Epitope Determination of SmSPI S. mansoni Serpin for Immunodiagnostic Application

The human parasitic disease Schistosomiasis is caused by the Schistosoma trematode flatworm that infects freshwaters in tropical regions of the world, particularly in Sub-Saharan Africa, South America, and the Far-East. It has also been observed as an emerging disease in Europe, due to increased imm...

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Bibliographic Details
Published in:	Vaccines (Basel) Vol. 9; no. 4; p. 322
Main Authors:	De Benedetti, Stefano, Di Pisa, Flavio, Fassi, Enrico Mario Alessandro, Cretich, Marina, Musicò, Angelo, Frigerio, Roberto, Mussida, Alessandro, Bombaci, Mauro, Grifantini, Renata, Colombo, Giorgio, Bolognesi, Martino, Grande, Romualdo, Zanchetta, Nadia, Gismondo, Maria Rita, Mileto, Davide, Mancon, Alessandro, Gourlay, Louise Jane
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.04.2021 MDPI
Subjects:	Antibodies Antigens Antisera Biomarkers Chromatography circulating antigen Crystal structure Crystallization Drug resistance Epitope mapping Fresh water Immigration Immunoreactivity in silico epitope predictions Infections Neglected Tropical Disease Parasites Parasitic diseases Pathogens Protease inhibitors Proteinase inhibitors Proteins Schistosoma Schistosoma mansoni Schistosomiasis Serine Serine protease inhibitor Serine proteinase Tropical diseases Tropical environment Tropical environments United States > US in silico epitope predictions Neglected Tropical Disease crystal structure circulating antigen immunodiagnostics schistosomiasis Serine protease inhibitor
ISSN:	2076-393X, 2076-393X
Online Access:	Get full text
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