Embryo-scale, single-cell spatial transcriptomics

Spatial patterns of gene expression manifest at scales ranging from local (e.g., cell-cell interactions) to global (e.g., body axis patterning). However, current spatial transcriptomics methods either average local contexts or are restricted to limited fields of view. Here, we introduce sci-Space, w...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 373; číslo 6550; s. 111
Hlavní autori:	Srivatsan, Sanjay R, Regier, Mary C, Barkan, Eliza, Franks, Jennifer M, Packer, Jonathan S, Grosjean, Parker, Duran, Madeleine, Saxton, Sarah, Ladd, Jon J, Spielmann, Malte, Lois, Carlos, Lampe, Paul D, Shendure, Jay, Stevens, Kelly R, Trapnell, Cole
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 02.07.2021
Predmet:	Animals Atlases as Topic Body Patterning - genetics Brain - embryology Cell Movement Embryo, Mammalian - embryology Embryonic Development - genetics Gene Expression Profiling - methods Mice Neurogenesis - genetics Neurons - cytology Single-Cell Analysis - methods Transcriptome
ISSN:	1095-9203, 1095-9203
On-line prístup:	Zistit podrobnosti o prístupe
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