Embryo-scale, single-cell spatial transcriptomics

Spatial patterns of gene expression manifest at scales ranging from local (e.g., cell-cell interactions) to global (e.g., body axis patterning). However, current spatial transcriptomics methods either average local contexts or are restricted to limited fields of view. Here, we introduce sci-Space, w...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 373; H. 6550; S. 111
Hauptverfasser:	Srivatsan, Sanjay R, Regier, Mary C, Barkan, Eliza, Franks, Jennifer M, Packer, Jonathan S, Grosjean, Parker, Duran, Madeleine, Saxton, Sarah, Ladd, Jon J, Spielmann, Malte, Lois, Carlos, Lampe, Paul D, Shendure, Jay, Stevens, Kelly R, Trapnell, Cole
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 02.07.2021
Schlagworte:	Animals Atlases as Topic Body Patterning - genetics Brain - embryology Cell Movement Embryo, Mammalian - embryology Embryonic Development - genetics Gene Expression Profiling - methods Mice Neurogenesis - genetics Neurons - cytology Single-Cell Analysis - methods Transcriptome
ISSN:	1095-9203, 1095-9203
Online-Zugang:	Weitere Angaben
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