Cell competition during reprogramming gives rise to dominant clones

The ability to generate induced pluripotent stem cells from differentiated cell types has enabled researchers to engineer cell states. Although studies have identified molecular networks that reprogram cells to pluripotency, the cellular dynamics of these processes remain poorly understood. Here, by...

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Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 364; no. 6438
Main Authors:	Shakiba, Nika, Fahmy, Ahmed, Jayakumaran, Gowtham, McGibbon, Sophie, David, Laurent, Trcka, Daniel, Elbaz, Judith, Puri, Mira C, Nagy, Andras, van der Kooy, Derek, Goyal, Sidhartha, Wrana, Jeffrey L, Zandstra, Peter W
Format:	Journal Article
Language:	English
Published:	United States 26.04.2019
Subjects:	Animals Cellular Reprogramming - genetics Cellular Reprogramming - physiology Cellular Reprogramming Techniques Clonal Evolution Clone Cells - cytology DNA - genetics Fibroblasts - cytology Induced Pluripotent Stem Cells - cytology Mice Models, Theoretical
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
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