S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

Innate lymphoid cells (ILCs) are innate counterparts of adaptive T lymphocytes, contributing to host defense, tissue repair, metabolic homeostasis, and inflammatory diseases. ILCs have been considered to be tissue-resident cells, but whether ILCs move between tissue sites during infection has been u...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 359; H. 6371; S. 114
Hauptverfasser:	Huang, Yuefeng, Mao, Kairui, Chen, Xi, Sun, Ming-An, Kawabe, Takeshi, Li, Weizhe, Usher, Nicholas, Zhu, Jinfang, Urban, Jr, Joseph F, Paul, William E, Germain, Ronald N
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 05.01.2018
Schlagworte:	Adaptive Immunity Animals Cell Proliferation Chemotaxis - immunology Female Fingolimod Hydrochloride - pharmacology Homeodomain Proteins - genetics Homeostasis Immunity, Innate Immunosuppressive Agents - pharmacology Interleukin-17 - immunology Intestines - immunology Lung - immunology Lymphocytes - immunology Lysophospholipids - immunology Mice Mice, Inbred C57BL Mice, Mutant Strains Mucous Membrane - immunology Nippostrongylus - immunology Sphingosine - analogs & derivatives Sphingosine - immunology Strongylida Infections - immunology T-Lymphocytes - immunology
ISSN:	1095-9203, 1095-9203
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