Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes

Pathogenic germline variants underlie up to 20% of ovarian cancer (OC) and are associated with varying degrees of risk for OC. For mutations in high-penetrance genes such as / , the role of risk-reducing bilateral salpingo-oophorectomy (RRSO) in cancer prevention is well-established and improves mor...

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Veröffentlicht in:	JCO oncology practice Jg. 18; H. 3; S. 201
Hauptverfasser:	Liu, Ying L, Breen, Kelsey, Catchings, Amanda, Ranganathan, Megha, Latham, Alicia, Goldfrank, Deborah J, Grisham, Rachel N, Long Roche, Kara, Frey, Melissa K, Chi, Dennis S, Abu-Rustum, Nadeem, Aghajanian, Carol, Offit, Kenneth, Stadler, Zsofia K
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2022
Schlagworte:	Female Genetic Predisposition to Disease Humans Mutation Ovarian Neoplasms - genetics Ovarian Neoplasms - prevention & control Ovarian Neoplasms - surgery Risk Factors Salpingo-oophorectomy
ISSN:	2688-1535, 2688-1535
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