New signaling pathways govern the host response to C. albicans infection in various niches

Candida albicans, the major invasive fungal pathogen of humans, can cause both debilitating mucosal infections and fatal invasive infections. Understanding the complex nature of the host-pathogen interaction in each of these contexts is essential to developing desperately needed therapies to treat f...

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Vydané v:	Genome research Ročník 25; číslo 5; s. 679 - 689
Hlavní autori:	Liu, Yaoping, Shetty, Amol C, Schwartz, Jennifer A, Bradford, L Latey, Xu, Wenjie, Phan, Qyunh T, Kumari, Priti, Mahurkar, Anup, Mitchell, Aaron P, Ravel, Jacques, Fraser, Claire M, Filler, Scott G, Bruno, Vincent M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.05.2015
Predmet:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Animals Candida albicans - pathogenicity Candidiasis - metabolism Human Umbilical Vein Endothelial Cells - metabolism Human Umbilical Vein Endothelial Cells - microbiology Humans Mice Mice, Inbred BALB C Phosphoproteins - genetics Phosphoproteins - metabolism Proto-Oncogene Proteins c-sis - genetics Proto-Oncogene Proteins c-sis - metabolism Signal Transduction Transcriptome
ISSN:	1549-5469
On-line prístup:	Zistit podrobnosti o prístupe
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