Clostridium butyricum, a butyrate-producing probiotic, inhibits intestinal tumor development through modulating Wnt signaling and gut microbiota

Gut microbiota dysbiosis is closely involved in intestinal carcinogenesis. A marked reduction in butyrate-producing bacteria has been observed in patients with colorectal cancer (CRC); nevertheless, the potential benefit of butyrate-producing bacteria against intestinal tumor development has not bee...

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Veröffentlicht in:	Cancer letters Jg. 469; S. 456 - 467
Hauptverfasser:	Chen, Danfeng, Jin, Duochen, Huang, Shumin, Wu, Jingyi, Xu, Mengque, Liu, Tianyu, Dong, Wenxiao, Liu, Xiang, Wang, Sinan, Zhong, Weilong, Liu, Yi, Jiang, Ruihuan, Piao, Meiyu, Wang, Bangmao, Cao, Hailong
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Clare Elsevier B.V 28.01.2020 Elsevier Limited
Schlagworte:	Adenoma Apcmin/+ mouse Apoptosis Bacteria Cancer Carcinogenesis Cecum Cell growth Cell proliferation Clostridium butyricum Colon Colorectal cancer Colorectal carcinoma Digestive system Discriminant analysis Dysbacteriosis Gastrointestinal tract Gene silencing Grants Gut microbiota High fat diet Inflammatory bowel disease Intestinal microflora Intestine Microbiota Mutation Pathogens Probiotics RNA-mediated interference Short-chain fatty acids Signal transduction siRNA Tumor cells Tumors Wnt protein Wnt signaling pathway β-Catenin China Gut microbiota Apcmin/+ mouse Short-chain fatty acids Wnt signaling pathway Clostridium butyricum
ISSN:	0304-3835, 1872-7980, 1872-7980
Online-Zugang:	Volltext
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