Dysregulated expression of matrix metalloproteinases and their inhibitors may participate in the pathogenesis of pre-eclampsia and fetal growth restriction

Trophoblast invasion into the maternal endometrium serves an important function in human pregnancy. Dysregulation of the finely controlled process of trophoblast invasion can result in a wide spectrum of pregnancy abnormalities. We aimed to elucidate the relationship between the expression of matrix...

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Vydané v:	Early human development Ročník 90; číslo 10; s. 657 - 664
Hlavní autori:	Zhu, JiaYu, Zhong, Mei, Pang, ZhanJun, Yu, YanHong
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Ireland Elsevier Ireland Ltd 01.10.2014
Predmet:	Advanced Basic Science Blotting, Western China Female Fetal growth restriction Fetal Growth Retardation - etiology Fetal Growth Retardation - physiopathology Gene Expression Regulation, Enzymologic - physiology Humans Immunohistochemistry Matrix metalloproteinase Matrix Metalloproteinases - metabolism Neonatal and Perinatal Medicine Placenta Placenta - cytology Placenta - metabolism Pre-eclampsia Pre-Eclampsia - etiology Pre-Eclampsia - physiopathology Pregnancy Statistics, Nonparametric Tissue inhibitor of metalloproteinase Tissue Inhibitor of Metalloproteinases - metabolism Trophoblast invasion Trophoblast-related diseases Trophoblasts - metabolism Trophoblasts - physiology China Trophoblast invasion Placenta Fetal growth restriction Tissue inhibitor of metalloproteinase Trophoblast-related diseases Matrix metalloproteinase Pre-eclampsia
ISSN:	0378-3782, 1872-6232, 1872-6232
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