TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

The transforming growth factor-β (TGF-β) is the prototype of the TGF-β family of growth and differentiation factors, which is encoded by 33 genes in mammals and comprises homo- and heterodimers. This review introduces the reader to the TGF-β family with its complexity of names and biological activit...

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Bibliographic Details
Published in:	Cold Spring Harbor perspectives in biology Vol. 8; no. 5
Main Authors:	Morikawa, Masato, Derynck, Rik, Miyazono, Kohei
Format:	Journal Article
Language:	English
Published:	United States 01.05.2016
Subjects:	Animals Cell Differentiation Cell Proliferation Disease Progression Fibrosis - metabolism Fibrosis - pathology Gene Expression Regulation Humans Immune System - metabolism Mice Neoplasms - metabolism Neoplasms - pathology Phylogeny Rats Signal Transduction Terminology as Topic Transforming Growth Factor beta - genetics Transforming Growth Factor beta - immunology Transforming Growth Factor beta - metabolism Transforming Growth Factor beta - physiology Wound Healing
ISSN:	1943-0264, 1943-0264
Online Access:	Get more information
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