Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy

To understand the molecular origins of diseases caused by ultraviolet and visible light, and also to develop photodynamic therapy, it is important to resolve the mechanism of photoinduced DNA damage. Damage to DNA bound to a photosensitizer molecule frequently proceeds by one-electron photo-oxidatio...

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Bibliographic Details
Published in:	Nature chemistry Vol. 7; no. 12; pp. 961 - 967
Main Authors:	Hall, James P., Poynton, Fergus E., Keane, Páraic M., Gurung, Sarah P., Brazier, John A., Cardin, David J., Winter, Graeme, Gunnlaugsson, Thorfinnur, Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Kelly, John M., Quinn, Susan J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.12.2015 Nature Publishing Group
Subjects:	140/125 639/638/440/56 639/638/440/947 Analytical Chemistry Biochemistry Chemistry Chemistry/Food Science Crystallography Crystallography, X-Ray Crystals Deoxyribonucleic acid DNA DNA - chemistry Electrons Guanine - chemistry Infrared spectroscopy Inorganic Chemistry Models, Molecular Organic Chemistry Oxidation Oxidation-Reduction Photooxidation Physical Chemistry Ruthenium Spectrophotometry, Infrared
ISSN:	1755-4330, 1755-4349, 1755-4349
Online Access:	Get full text
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