Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer

Epithelial to mesenchymal transition (EMT) of cancer cells involves loss of epithelial polarity and adhesiveness, and gain of invasive and migratory mesenchymal behaviours. EMT occurs in prostate cancer (PCa) but it is unknown whether this is in specific areas of primary tumours. We examined whether...

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Vydáno v:	Oncotarget Ročník 7; číslo 2; s. 1107
Hlavní autoři:	Verrill, Clare, Cerundolo, Lucia, Mckee, Chad, White, Michael, Kartsonaki, Christiana, Fryer, Eve, Morris, Emma, Brewster, Simon, Ratnayaka, Indrika, Marsden, Luke, Lilja, Hans, Muschel, Ruth, Lu, Xin, Hamdy, Freddie, Bryant, Richard J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 12.01.2016
Témata:	Actins - biosynthesis Aged Animals Cadherins - biosynthesis Cell Line, Tumor Epithelial-Mesenchymal Transition Humans Immunohistochemistry Male Mice, Knockout Middle Aged Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Snail Family Transcription Factors - biosynthesis Tissue Array Analysis epithelial to mesenchymal transition in vivo mouse prostate cancer model Pathology Section immunohistochemistry in vitro organotypic cell culture extraprostatic prostate cancer
ISSN:	1949-2553, 1949-2553
On-line přístup:	Zjistit podrobnosti o přístupu
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