Inflammation, endothelium, and coagulation in sepsis

Sepsis is a systemic response to infection, and symptoms are produced by host defense systems rather than by the invading pathogens. Amongst the most prominent features of sepsis, contributing significantly to its outcome, is activation of coagulation with concurrent down‐regulation of anticoagulant...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 83; no. 3; pp. 536 - 545
Main Authors:	Schouten, Marcel, Wiersinga, Willem Joost, Levi, Marcel, Poll, Tom
Format:	Journal Article
Language:	English
Published:	United States Society for Leukocyte Biology 01.03.2008
Subjects:	Anticoagulants - therapeutic use Blood Coagulation - physiology Blood Platelets - physiology Endothelium, Vascular - physiopathology Fibrinolysis Heparin - therapeutic use Humans infection Inflammation - blood Inflammation - physiopathology microparticles Models, Biological protease‐activated receptors protein C Sepsis - blood Sepsis - physiopathology Thromboplastin - physiology tissue factor von Willebrand Factor - physiology
ISSN:	0741-5400, 1938-3673
Online Access:	Get full text
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