Correlation of serotonin levels in CSF, platelets, plasma, and urine

Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. Samples were collected from humans and rats. Eighteen women age 38–51years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets,...

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Published in:Biochimica et biophysica acta Vol. 1820; no. 10; pp. 1496 - 1501
Main Authors: Audhya, Tapan, Adams, James B., Johansen, Leah
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01.10.2012
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ISSN:0304-4165, 0006-3002, 1872-8006
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Abstract Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. Samples were collected from humans and rats. Eighteen women age 38–51years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague–Dawley rats, adult male, 6months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction. For serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans). This method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF. ► An improved method of measuring serotonin levels was developed. ► Levels of serotonin in CSF and platelets were highly correlated in humans (r=0.97). ► First study to show high correlation of serotonin in CSF and blood in humans ► Levels of serotonin in CSF and platelets were highly correlated in rats (r=0.97). ► Lower correlations were found for serotonin in CSF vs. plasma or urine.
AbstractList BACKGROUND: Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. METHODS: Samples were collected from humans and rats. Eighteen women age 38–51years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague–Dawley rats, adult male, 6months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction. RESULTS: For serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans). GENERAL SIGNIFICANCE: This method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF.
Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. Samples were collected from humans and rats. Eighteen women age 38–51years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague–Dawley rats, adult male, 6months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction. For serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans). This method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF. ► An improved method of measuring serotonin levels was developed. ► Levels of serotonin in CSF and platelets were highly correlated in humans (r=0.97). ► First study to show high correlation of serotonin in CSF and blood in humans ► Levels of serotonin in CSF and platelets were highly correlated in rats (r=0.97). ► Lower correlations were found for serotonin in CSF vs. plasma or urine.
Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure.BACKGROUNDNeurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure.Samples were collected from humans and rats. Eighteen women age 38-51 years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague-Dawley rats, adult male, 6 months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction.METHODSSamples were collected from humans and rats. Eighteen women age 38-51 years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague-Dawley rats, adult male, 6 months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction.For serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans).RESULTSFor serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans).This method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF.GENERAL SIGNIFICANCEThis method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF.
Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. Samples were collected from humans and rats. Eighteen women age 38-51 years with fibromyalgia provided samples of CSF, plasma, platelets, and urine. Samples of CSF, plasma, platelets, and urine were also collected from Sprague-Dawley rats, adult male, 6 months old. One group of rats was treated with p-chlorophenylalanine to decrease their levels of serotonin, and another group of rats was treated with amphetamine to increase their levels of serotonin. Methodological improvements include: 1) the use of siliconized glassware, plasticware, and tubing to prevent adsorption of serotonin, 2) the extraction of serotonin from the CSF, plasma, and platelets, 3) repeated washing of the platelets with an improved buffer, and 4) early morning sample collection. HPLC/MS was used to measure serotonin after extraction. For serotonin, the new method of measuring platelet levels resulted in a very high correlation with levels of serotonin in CSF in rats (r=0.97) and humans (r=0.97). There were lower correlations of levels of serotonin in CSF with levels in plasma (r=0.77 for rats and r=0.57 in humans) and urine (r=0.67 in rats and r=0.62 in humans). This method of measuring serotonin levels in platelets results in a very strong correlation with levels in CSF, so in most cases platelet measurements will be preferable since it is much less invasive to collect. Levels of serotonin in plasma and urine are significantly but less strongly correlated with levels in CSF.
Author Adams, James B.
Audhya, Tapan
Johansen, Leah
Author_xml – sequence: 1
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  surname: Audhya
  fullname: Audhya, Tapan
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  organization: Materials Science and Engineering Program, Arizona State University, Tempe, AZ, USA
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  givenname: Leah
  surname: Johansen
  fullname: Johansen, Leah
  organization: Materials Science and Engineering Program, Arizona State University, Tempe, AZ, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/22664303$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1093/clinchem/27.5.775
10.1093/ajcn/75.3.561
10.1016/0024-3205(85)90406-0
10.1016/0304-3940(80)90167-6
10.1159/000054908
10.1007/s10545-005-0153-3
10.1111/j.1471-4159.1990.tb02319.x
10.1016/0278-5846(83)90101-X
10.1093/clinchem/30.5.815
10.1016/j.jelechem.2009.12.020
10.1016/0024-3205(90)90349-V
10.1136/jcp.26.8.635
10.1111/j.1476-5381.1979.tb07878.x
10.1016/S0361-9230(02)00866-3
10.1111/j.1530-0277.1982.tb05017.x
10.1016/S0278-5846(99)00069-X
10.1007/s00216-010-3466-5
10.1007/s00535-009-0167-y
10.1007/s00406-009-0092-3
10.1016/S0016-5085(85)80137-2
10.1093/clinchem/37.7.1178
10.1124/mi.10.4.6
10.1007/BF01952193
10.1046/j.1468-2982.1988.0801007.x
10.1016/S0165-1781(00)00129-3
10.1016/0024-3205(92)90221-A
10.1093/clinchem/42.7.1086
10.1093/clinchem/48.2.323
10.1093/clinchem/28.4.624
10.1016/S0161-813X(03)00085-8
10.1093/ajcn/42.4.639
10.1016/0024-3205(93)90237-W
10.1177/000456328402100515
10.1016/j.brainres.2006.04.026
10.1016/S0021-9673(00)82092-0
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Keywords Urine
Human
Plasma
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Serotonin
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References Rotman (bb0020) 1983; 7
Kumar, Kumar, Deepika, Fernandez, Eisdorfer (bb0140) 1990; 47
Von Hahn, Honegger, Pletscher (bb0035) 1980; 20
Artigas, Sarrias, Martinez, GelpIi (bb0105) 1985; 37
Engbaek, Voldby (bb0090) 1982; 28
Jernej, Banović, Cicin-Sain, Hranilović, Balija, Oresković, Folnegović-Smalc (bb0055) May 15 2000; 94
Anderson, Young, Cohen, Schlicht, Patel (bb0130) 1981; 27
Chauveau, Fert, Morel, Delaage (bb0110) 1991; 37
Oades, Daniels (bb0180) Nov 1999; 23
Lieber, DeCarli (bb0115) 1982; 6
Semerdjian-Rouquier, Bossi, Scatton (bb0195) 1981; 218
Stahl (bb0015) 1985; 21
Yan, Urano, Pietraszek, Shimoyama, Uemura, Kojima, Sakakibara, Serizawa, Takada, Takada (bb0070) 1993; 52
De la Calle, Paíno (bb0120) 2002; 59
Anderson, Feibel, Wetlaufer, Schlicht, Ort, Cohen (bb0050) Jan 1985; 88
de Jong, Wilkens, de Vries, Kema (bb0210) Apr 2010; 396
Nagatsu (bb0040) Jan 2004; 25
Pussard, Guigueno, Adam, Giudicelli (bb0085) 1996; 42
Mercado (bb0030) Aug 2010; 10
Sarrias, Cabré, Martínez, Artigas (bb0060) 1990; 54
Kushnir, Urry, Frank, Roberts, Shushan (bb0135) 2002; 48
Kumar, Berger, Eisdorfer, Fernandez, Goodkin, Kumar (bb0145) 2001; 44
Malmgren, Hasselmark (bb0025) 1988; 8
Kepa, Oczko-Grzesik, Badura-Glombik (bb0155) 2008; 62
Da Prada, Cesura, Launay, Richards (bb0010) 1988; 44
Ganguly, Sonnichsen (bb0080) 1973; 26
Liu, Xiang, Zhou, Ding (bb0075) 2010; 640
Goldstein, Stull, Zimlichman, Levinson, Smith, Keiser (bb0125) 1984; 30
Hou, Jia, Liu, Li (bb0200) Jun 20 2006; 1095
Ormazabal, Vilaseca, Pérez-Dueñas, Lambruschini, Gómez, Campistol, Artuch (bb0160) 2005; 28
Ehrlich, Franke, Scherag, Burghardt, Schott, Schneider, Brockhaus, Hein, Uebelhack, Lehmkuhl (bb0170) Sep 2010; 260
Pietraszek, Takada, Yan, Urano, Serizawa, Takada (bb0065) 1992; 51
Da Prada, Picotti (bb0005) 1979; 65
Franke, Schmidtmann, Riedl, van der Voort, Uebelhack, Mönnikes (bb0205) Apr 2010; 45
Feldman, Lee (bb0045) 1985; 42
Remer, Neubert, Maser-Gluth (bb0190) Mar 2002; 75
Kwarts, Kwarts, Rutgers (bb0175) Sep 1984; 21
Da Prada (10.1016/j.bbagen.2012.05.012_bb0010) 1988; 44
Nagatsu (10.1016/j.bbagen.2012.05.012_bb0040) 2004; 25
Anderson (10.1016/j.bbagen.2012.05.012_bb0130) 1981; 27
Lieber (10.1016/j.bbagen.2012.05.012_bb0115) 1982; 6
Chauveau (10.1016/j.bbagen.2012.05.012_bb0110) 1991; 37
Jernej (10.1016/j.bbagen.2012.05.012_bb0055) 2000; 94
Liu (10.1016/j.bbagen.2012.05.012_bb0075) 2010; 640
Oades (10.1016/j.bbagen.2012.05.012_bb0180) 1999; 23
Kepa (10.1016/j.bbagen.2012.05.012_bb0155) 2008; 62
Malmgren (10.1016/j.bbagen.2012.05.012_bb0025) 1988; 8
Ormazabal (10.1016/j.bbagen.2012.05.012_bb0160) 2005; 28
Remer (10.1016/j.bbagen.2012.05.012_bb0190) 2002; 75
Feldman (10.1016/j.bbagen.2012.05.012_bb0045) 1985; 42
Franke (10.1016/j.bbagen.2012.05.012_bb0205) 2010; 45
Sarrias (10.1016/j.bbagen.2012.05.012_bb0060) 1990; 54
Ganguly (10.1016/j.bbagen.2012.05.012_bb0080) 1973; 26
de Jong (10.1016/j.bbagen.2012.05.012_bb0210) 2010; 396
Engbaek (10.1016/j.bbagen.2012.05.012_bb0090) 1982; 28
Goldstein (10.1016/j.bbagen.2012.05.012_bb0125) 1984; 30
Anderson (10.1016/j.bbagen.2012.05.012_bb0050) 1985; 88
Kumar (10.1016/j.bbagen.2012.05.012_bb0140) 1990; 47
De la Calle (10.1016/j.bbagen.2012.05.012_bb0120) 2002; 59
Kumar (10.1016/j.bbagen.2012.05.012_bb0145) 2001; 44
Rotman (10.1016/j.bbagen.2012.05.012_bb0020) 1983; 7
Pussard (10.1016/j.bbagen.2012.05.012_bb0085) 1996; 42
Semerdjian-Rouquier (10.1016/j.bbagen.2012.05.012_bb0195) 1981; 218
Von Hahn (10.1016/j.bbagen.2012.05.012_bb0035) 1980; 20
Kushnir (10.1016/j.bbagen.2012.05.012_bb0135) 2002; 48
Hou (10.1016/j.bbagen.2012.05.012_bb0200) 2006; 1095
Stahl (10.1016/j.bbagen.2012.05.012_bb0015) 1985; 21
Da Prada (10.1016/j.bbagen.2012.05.012_bb0005) 1979; 65
Mercado (10.1016/j.bbagen.2012.05.012_bb0030) 2010; 10
Yan (10.1016/j.bbagen.2012.05.012_bb0070) 1993; 52
Artigas (10.1016/j.bbagen.2012.05.012_bb0105) 1985; 37
Ehrlich (10.1016/j.bbagen.2012.05.012_bb0170) 2010; 260
Kwarts (10.1016/j.bbagen.2012.05.012_bb0175) 1984; 21
Pietraszek (10.1016/j.bbagen.2012.05.012_bb0065) 1992; 51
References_xml – volume: 21
  start-page: 663
  year: 1985
  end-page: 671
  ident: bb0015
  article-title: Peripheral models for the study of neurotransmitter receptors in man
  publication-title: Psychopharmacol. Bull.
– volume: 37
  start-page: 441
  year: 1985
  end-page: 447
  ident: bb0105
  article-title: Serotonin in body fluids: characterization of human plasmatic and cerebrospinal fluid pools by means of a new HPLC method
  publication-title: Life Sci.
– volume: 218
  start-page: 663
  year: 1981
  end-page: 670
  ident: bb0195
  article-title: Determination of 5-hydroxytryptophan, serotonin and 5-hydroxyindoleacetic acid in rat and human brain and biological fluids by reversed-phase high-performance liquid chromatography with electrochemical detection
  publication-title: J. Chromatogr.
– volume: 42
  start-page: 639
  year: 1985
  end-page: 643
  ident: bb0045
  article-title: Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid
  publication-title: Am. J. Clin. Nutr.
– volume: 27
  start-page: 775
  year: 1981
  end-page: 776
  ident: bb0130
  article-title: Liquid-chromatographic determination of serotonin and tryptophan in whole blood and plasma
  publication-title: Clin. Chem.
– volume: 54
  start-page: 783
  year: 1990
  end-page: 786
  ident: bb0060
  article-title: Relationship between serotoninergic measures in blood and cerebrospinal fluid simultaneously obtained in humans
  publication-title: J. Neurochem.
– volume: 42
  start-page: 1086
  year: 1996
  end-page: 1091
  ident: bb0085
  article-title: Validation of HPLC-amperometric detection to measure serotonin in plasma, platelets, whole blood, and urine
  publication-title: Clin. Chem.
– volume: 75
  start-page: 561
  year: Mar 2002
  end-page: 569
  ident: bb0190
  article-title: Anthropometry-based reference values for 24 hour urinary creatinine excretion during growth and their use in endocrine and nutritional research
  publication-title: Am. J. Clin. Nutr.
– volume: 6
  start-page: 523
  year: 1982
  end-page: 531
  ident: bb0115
  article-title: The feeding of alcohol in liquid diets: two decades of applications and 1982 update
  publication-title: Alcohol. Clin. Exp. Res.
– volume: 30
  start-page: 815
  year: 1984
  end-page: 816
  ident: bb0125
  article-title: Simultaneous measurement of DOPA, DOPAC, and catecholamines in plasma by liquid chromatography with electrochemical detection
  publication-title: Clin. Chem.
– volume: 8
  start-page: 7
  year: 1988
  end-page: 24
  ident: bb0025
  article-title: The platelet and the neuron: two cells in focus in migraine
  publication-title: Cephalalgia
– volume: 44
  start-page: 13
  year: 2001
  end-page: 18
  ident: bb0145
  article-title: Cerebrospinal fluid 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in HIV-1 infection
  publication-title: Neuropsychobiology
– volume: 26
  start-page: 635
  year: 1973
  end-page: 637
  ident: bb0080
  article-title: Technical methods. A simple method for the isolation of blood platelets
  publication-title: J. Clin. Pathol.
– volume: 59
  start-page: 245
  year: 2002
  end-page: 250
  ident: bb0120
  article-title: A procedure for direct lumbar puncture in rats
  publication-title: Brain Res. Bull.
– volume: 7
  start-page: 135
  year: 1983
  end-page: 151
  ident: bb0020
  article-title: Blood platelets in psychopharmacological research
  publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry
– volume: 396
  start-page: 2609
  year: Apr 2010
  end-page: 2616
  ident: bb0210
  article-title: Automated mass spectrometric analysis of urinary and plasma serotonin
  publication-title: Anal. Bioanal. Chem.
– volume: 52
  start-page: 745
  year: 1993
  end-page: 749
  ident: bb0070
  article-title: Correlation between serotonergic measures in cerebrospinal fluid and blood of subhuman primate
  publication-title: Life Sci.
– volume: 20
  start-page: 319
  year: 1980
  end-page: 322
  ident: bb0035
  article-title: Similar kinetic characteristics of 5-hydroxytryptamine binding in blood platelets and brain membranes of rats
  publication-title: Neurosci. Lett.
– volume: 88
  start-page: 86
  year: Jan 1985
  end-page: 89
  ident: bb0050
  article-title: Effect of a meal on human whole blood serotonin
  publication-title: Gastroenterology
– volume: 51
  start-page: 75
  year: 1992
  end-page: 82
  ident: bb0065
  article-title: Relationship between serotonergic measures in periphery and the brain of mouse
  publication-title: Life Sci.
– volume: 21
  start-page: 425
  year: Sep 1984
  end-page: 429
  ident: bb0175
  article-title: A simple paired-ion liquid chromatography assay for serotonin in cerebrospinal fluid, platelet-rich plasma, serum and urine
  publication-title: Ann. Clin. Biochem.
– volume: 28
  start-page: 624
  year: 1982
  end-page: 628
  ident: bb0090
  article-title: Radioimmunoassay of serotonin (5-hydroxytryptamine) in cerebrospinal fluid, plasma, and serum
  publication-title: Clin. Chem.
– volume: 62
  start-page: 793
  year: 2008
  end-page: 800
  ident: bb0155
  article-title: Evaluation of cerebrospinal fluid serotonin (5-HT) concentration in patients with post-Lyme disease syndrome—preliminary study
  publication-title: Przegl. Epidemiol.
– volume: 260
  start-page: 483
  year: Sep 2010
  end-page: 490
  ident: bb0170
  article-title: The 5-HTTLPR polymorphism, platelet serotonin transporter activity and platelet serotonin content in underweight and weight-recovered females with anorexia nervosa
  publication-title: Eur. Arch. Psychiatry Clin. Neurosci.
– volume: 44
  start-page: 115
  year: 1988
  end-page: 126
  ident: bb0010
  article-title: Platelets as a model for neurones?
  publication-title: Experientia
– volume: 94
  start-page: 153
  year: May 15 2000
  end-page: 162
  ident: bb0055
  article-title: Physiological characteristics of platelet/circulatory serotonin: study on a large human population
  publication-title: Psychiatry Res.
– volume: 45
  start-page: 389
  year: Apr 2010
  end-page: 398
  ident: bb0205
  article-title: Serotonin transporter activity and serotonin concentration in platelets of patients with irritable bowel syndrome: effect of gender
  publication-title: J. Gastroenterol.
– volume: 37
  start-page: 1178
  year: 1991
  end-page: 1184
  ident: bb0110
  article-title: Rapid and specific enzyme immunoassay of serotonin
  publication-title: Clin. Chem.
– volume: 640
  start-page: 1
  year: 2010
  end-page: 7
  ident: bb0075
  article-title: A disposable amperometric sensor for rapid detection of serotonin in the blood and brain of the depressed mice based on Nafion membrane-coated colloidal gold screen-printed electrode
  publication-title: J. Electroanal. Chem.
– volume: 23
  start-page: 1329
  year: Nov 1999
  end-page: 1344
  ident: bb0180
  article-title: Subclinical polydipsia and polyuria in young patients with schizophrenia or obsessive–compulsive disorder vs normal controls
  publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry
– volume: 65
  start-page: 653
  year: 1979
  end-page: 662
  ident: bb0005
  article-title: Content and subcellular localization of catecholamines and 5-hydroxytryptamine in human and animal blood platelets: monoamine distribution between platelets and plasma
  publication-title: Br. J. Pharmacol.
– volume: 10
  start-page: 231
  year: Aug 2010
  end-page: 241
  ident: bb0030
  article-title: Kilic F Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels
  publication-title: Mol. Interv.
– volume: 28
  start-page: 863
  year: 2005
  end-page: 870
  ident: bb0160
  article-title: Platelet serotonin concentrations in PKU patients under dietary control and tetrahydrobiopterin treatment
  publication-title: J. Inherit. Metab. Dis.
– volume: 48
  start-page: 323
  year: 2002
  end-page: 331
  ident: bb0135
  article-title: Analysis of catecholamines in urine by positive-ion electrospray tandem mass spectrometry
  publication-title: Clin. Chem.
– volume: 1095
  start-page: 154
  year: Jun 20 2006
  end-page: 158
  ident: bb0200
  article-title: CSF serotonin, 5-hydroxyindolacetic acid and neuropeptide Y levels in severe major depressive disorder
  publication-title: Brain Res.
– volume: 47
  start-page: 1751
  year: 1990
  end-page: 1759
  ident: bb0140
  article-title: A modified HPLC technique for simultaneous measurement of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in cerebrospinal fluid, platelet and plasma
  publication-title: Life Sci.
– volume: 25
  start-page: 11
  year: Jan 2004
  end-page: 20
  ident: bb0040
  article-title: Progress in monoamine oxidase (MAO) research in relation to genetic engineering
  publication-title: Neurotoxicology
– volume: 27
  start-page: 775
  issue: 5
  year: 1981
  ident: 10.1016/j.bbagen.2012.05.012_bb0130
  article-title: Liquid-chromatographic determination of serotonin and tryptophan in whole blood and plasma
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/27.5.775
– volume: 75
  start-page: 561
  issue: 3
  year: 2002
  ident: 10.1016/j.bbagen.2012.05.012_bb0190
  article-title: Anthropometry-based reference values for 24 hour urinary creatinine excretion during growth and their use in endocrine and nutritional research
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/75.3.561
– volume: 21
  start-page: 663
  issue: 3
  year: 1985
  ident: 10.1016/j.bbagen.2012.05.012_bb0015
  article-title: Peripheral models for the study of neurotransmitter receptors in man
  publication-title: Psychopharmacol. Bull.
– volume: 37
  start-page: 441
  year: 1985
  ident: 10.1016/j.bbagen.2012.05.012_bb0105
  article-title: Serotonin in body fluids: characterization of human plasmatic and cerebrospinal fluid pools by means of a new HPLC method
  publication-title: Life Sci.
  doi: 10.1016/0024-3205(85)90406-0
– volume: 20
  start-page: 319
  year: 1980
  ident: 10.1016/j.bbagen.2012.05.012_bb0035
  article-title: Similar kinetic characteristics of 5-hydroxytryptamine binding in blood platelets and brain membranes of rats
  publication-title: Neurosci. Lett.
  doi: 10.1016/0304-3940(80)90167-6
– volume: 62
  start-page: 793
  issue: 4
  year: 2008
  ident: 10.1016/j.bbagen.2012.05.012_bb0155
  article-title: Evaluation of cerebrospinal fluid serotonin (5-HT) concentration in patients with post-Lyme disease syndrome—preliminary study
  publication-title: Przegl. Epidemiol.
– volume: 44
  start-page: 13
  issue: 1
  year: 2001
  ident: 10.1016/j.bbagen.2012.05.012_bb0145
  article-title: Cerebrospinal fluid 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in HIV-1 infection
  publication-title: Neuropsychobiology
  doi: 10.1159/000054908
– volume: 28
  start-page: 863
  issue: 6
  year: 2005
  ident: 10.1016/j.bbagen.2012.05.012_bb0160
  article-title: Platelet serotonin concentrations in PKU patients under dietary control and tetrahydrobiopterin treatment
  publication-title: J. Inherit. Metab. Dis.
  doi: 10.1007/s10545-005-0153-3
– volume: 54
  start-page: 783
  year: 1990
  ident: 10.1016/j.bbagen.2012.05.012_bb0060
  article-title: Relationship between serotoninergic measures in blood and cerebrospinal fluid simultaneously obtained in humans
  publication-title: J. Neurochem.
  doi: 10.1111/j.1471-4159.1990.tb02319.x
– volume: 7
  start-page: 135
  year: 1983
  ident: 10.1016/j.bbagen.2012.05.012_bb0020
  article-title: Blood platelets in psychopharmacological research
  publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry
  doi: 10.1016/0278-5846(83)90101-X
– volume: 30
  start-page: 815
  year: 1984
  ident: 10.1016/j.bbagen.2012.05.012_bb0125
  article-title: Simultaneous measurement of DOPA, DOPAC, and catecholamines in plasma by liquid chromatography with electrochemical detection
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/30.5.815
– volume: 640
  start-page: 1
  year: 2010
  ident: 10.1016/j.bbagen.2012.05.012_bb0075
  article-title: A disposable amperometric sensor for rapid detection of serotonin in the blood and brain of the depressed mice based on Nafion membrane-coated colloidal gold screen-printed electrode
  publication-title: J. Electroanal. Chem.
  doi: 10.1016/j.jelechem.2009.12.020
– volume: 47
  start-page: 1751
  issue: 19
  year: 1990
  ident: 10.1016/j.bbagen.2012.05.012_bb0140
  article-title: A modified HPLC technique for simultaneous measurement of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in cerebrospinal fluid, platelet and plasma
  publication-title: Life Sci.
  doi: 10.1016/0024-3205(90)90349-V
– volume: 26
  start-page: 635
  year: 1973
  ident: 10.1016/j.bbagen.2012.05.012_bb0080
  article-title: Technical methods. A simple method for the isolation of blood platelets
  publication-title: J. Clin. Pathol.
  doi: 10.1136/jcp.26.8.635
– volume: 65
  start-page: 653
  year: 1979
  ident: 10.1016/j.bbagen.2012.05.012_bb0005
  article-title: Content and subcellular localization of catecholamines and 5-hydroxytryptamine in human and animal blood platelets: monoamine distribution between platelets and plasma
  publication-title: Br. J. Pharmacol.
  doi: 10.1111/j.1476-5381.1979.tb07878.x
– volume: 59
  start-page: 245
  year: 2002
  ident: 10.1016/j.bbagen.2012.05.012_bb0120
  article-title: A procedure for direct lumbar puncture in rats
  publication-title: Brain Res. Bull.
  doi: 10.1016/S0361-9230(02)00866-3
– volume: 6
  start-page: 523
  year: 1982
  ident: 10.1016/j.bbagen.2012.05.012_bb0115
  article-title: The feeding of alcohol in liquid diets: two decades of applications and 1982 update
  publication-title: Alcohol. Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.1982.tb05017.x
– volume: 23
  start-page: 1329
  issue: 8
  year: 1999
  ident: 10.1016/j.bbagen.2012.05.012_bb0180
  article-title: Subclinical polydipsia and polyuria in young patients with schizophrenia or obsessive–compulsive disorder vs normal controls
  publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry
  doi: 10.1016/S0278-5846(99)00069-X
– volume: 396
  start-page: 2609
  issue: 7
  year: 2010
  ident: 10.1016/j.bbagen.2012.05.012_bb0210
  article-title: Automated mass spectrometric analysis of urinary and plasma serotonin
  publication-title: Anal. Bioanal. Chem.
  doi: 10.1007/s00216-010-3466-5
– volume: 45
  start-page: 389
  issue: 4
  year: 2010
  ident: 10.1016/j.bbagen.2012.05.012_bb0205
  article-title: Serotonin transporter activity and serotonin concentration in platelets of patients with irritable bowel syndrome: effect of gender
  publication-title: J. Gastroenterol.
  doi: 10.1007/s00535-009-0167-y
– volume: 260
  start-page: 483
  issue: 6
  year: 2010
  ident: 10.1016/j.bbagen.2012.05.012_bb0170
  article-title: The 5-HTTLPR polymorphism, platelet serotonin transporter activity and platelet serotonin content in underweight and weight-recovered females with anorexia nervosa
  publication-title: Eur. Arch. Psychiatry Clin. Neurosci.
  doi: 10.1007/s00406-009-0092-3
– volume: 88
  start-page: 86
  issue: 1 Pt 1
  year: 1985
  ident: 10.1016/j.bbagen.2012.05.012_bb0050
  article-title: Effect of a meal on human whole blood serotonin
  publication-title: Gastroenterology
  doi: 10.1016/S0016-5085(85)80137-2
– volume: 37
  start-page: 1178
  year: 1991
  ident: 10.1016/j.bbagen.2012.05.012_bb0110
  article-title: Rapid and specific enzyme immunoassay of serotonin
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/37.7.1178
– volume: 10
  start-page: 231
  issue: 4
  year: 2010
  ident: 10.1016/j.bbagen.2012.05.012_bb0030
  article-title: Kilic F Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels
  publication-title: Mol. Interv.
  doi: 10.1124/mi.10.4.6
– volume: 44
  start-page: 115
  year: 1988
  ident: 10.1016/j.bbagen.2012.05.012_bb0010
  article-title: Platelets as a model for neurones?
  publication-title: Experientia
  doi: 10.1007/BF01952193
– volume: 8
  start-page: 7
  year: 1988
  ident: 10.1016/j.bbagen.2012.05.012_bb0025
  article-title: The platelet and the neuron: two cells in focus in migraine
  publication-title: Cephalalgia
  doi: 10.1046/j.1468-2982.1988.0801007.x
– volume: 94
  start-page: 153
  issue: 2
  year: 2000
  ident: 10.1016/j.bbagen.2012.05.012_bb0055
  article-title: Physiological characteristics of platelet/circulatory serotonin: study on a large human population
  publication-title: Psychiatry Res.
  doi: 10.1016/S0165-1781(00)00129-3
– volume: 51
  start-page: 75
  year: 1992
  ident: 10.1016/j.bbagen.2012.05.012_bb0065
  article-title: Relationship between serotonergic measures in periphery and the brain of mouse
  publication-title: Life Sci.
  doi: 10.1016/0024-3205(92)90221-A
– volume: 42
  start-page: 1086
  year: 1996
  ident: 10.1016/j.bbagen.2012.05.012_bb0085
  article-title: Validation of HPLC-amperometric detection to measure serotonin in plasma, platelets, whole blood, and urine
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/42.7.1086
– volume: 48
  start-page: 323
  year: 2002
  ident: 10.1016/j.bbagen.2012.05.012_bb0135
  article-title: Analysis of catecholamines in urine by positive-ion electrospray tandem mass spectrometry
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/48.2.323
– volume: 28
  start-page: 624
  year: 1982
  ident: 10.1016/j.bbagen.2012.05.012_bb0090
  article-title: Radioimmunoassay of serotonin (5-hydroxytryptamine) in cerebrospinal fluid, plasma, and serum
  publication-title: Clin. Chem.
  doi: 10.1093/clinchem/28.4.624
– volume: 25
  start-page: 11
  issue: 1–2
  year: 2004
  ident: 10.1016/j.bbagen.2012.05.012_bb0040
  article-title: Progress in monoamine oxidase (MAO) research in relation to genetic engineering
  publication-title: Neurotoxicology
  doi: 10.1016/S0161-813X(03)00085-8
– volume: 42
  start-page: 639
  year: 1985
  ident: 10.1016/j.bbagen.2012.05.012_bb0045
  article-title: Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/42.4.639
– volume: 52
  start-page: 745
  year: 1993
  ident: 10.1016/j.bbagen.2012.05.012_bb0070
  article-title: Correlation between serotonergic measures in cerebrospinal fluid and blood of subhuman primate
  publication-title: Life Sci.
  doi: 10.1016/0024-3205(93)90237-W
– volume: 21
  start-page: 425
  issue: Pt 5
  year: 1984
  ident: 10.1016/j.bbagen.2012.05.012_bb0175
  article-title: A simple paired-ion liquid chromatography assay for serotonin in cerebrospinal fluid, platelet-rich plasma, serum and urine
  publication-title: Ann. Clin. Biochem.
  doi: 10.1177/000456328402100515
– volume: 1095
  start-page: 154
  issue: 1
  year: 2006
  ident: 10.1016/j.bbagen.2012.05.012_bb0200
  article-title: CSF serotonin, 5-hydroxyindolacetic acid and neuropeptide Y levels in severe major depressive disorder
  publication-title: Brain Res.
  doi: 10.1016/j.brainres.2006.04.026
– volume: 218
  start-page: 663
  year: 1981
  ident: 10.1016/j.bbagen.2012.05.012_bb0195
  article-title: Determination of 5-hydroxytryptophan, serotonin and 5-hydroxyindoleacetic acid in rat and human brain and biological fluids by reversed-phase high-performance liquid chromatography with electrochemical detection
  publication-title: J. Chromatogr.
  doi: 10.1016/S0021-9673(00)82092-0
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Snippet Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. Samples were collected from humans and...
BACKGROUND: Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure. METHODS: Samples were...
Neurotransmitter levels are best measured in the cerebrospinal fluid (CSF), but that requires an invasive procedure.BACKGROUNDNeurotransmitter levels are best...
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SubjectTerms adsorption
Adult
adults
amphetamine
Animals
Blood Platelets - chemistry
Blood Platelets - metabolism
Cerebrospinal fluid
Chromatography, High Pressure Liquid
Female
high performance liquid chromatography
Human
Humans
Male
males
Middle Aged
Plasma
Platelet
platelets
Rats
Rats, Sprague-Dawley
Serotonin
Serotonin - blood
Serotonin - cerebrospinal fluid
Serotonin - metabolism
Serotonin - urine
Specimen Handling - methods
Urine
Validation Studies as Topic
washing
women
Title Correlation of serotonin levels in CSF, platelets, plasma, and urine
URI https://dx.doi.org/10.1016/j.bbagen.2012.05.012
https://www.ncbi.nlm.nih.gov/pubmed/22664303
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