A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed

Bioenergetic failure caused by impaired utilisation of glucose and fatty acids contributes to organ dysfunction across multiple tissues in critical illness. Ketone bodies may form an alternative substrate source, but the feasibility and safety of inducing a ketogenic state in physiologically unstabl...

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Veröffentlicht in:	Nature communications Jg. 14; H. 1; S. 8345 - 14
Hauptverfasser:	McNelly, Angela, Langan, Anne, Bear, Danielle E., Page, Alexandria, Martin, Tim, Seidu, Fatima, Santos, Filipa, Rooney, Kieron, Liang, Kaifeng, Heales, Simon J., Baldwin, Tomas, Alldritt, Isabelle, Crossland, Hannah, Atherton, Philip J., Wilkinson, Daniel, Montgomery, Hugh, Prowle, John, Pearse, Rupert, Eaton, Simon, Puthucheary, Zudin A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 15.12.2023 Nature Publishing Group Nature Portfolio
Schlagworte:	101/58 692/308/153 692/308/2779/109/1940 692/308/575 Adult Amino acids Bioenergetics Clinical trials Critical Illness Diarrhea Enteral feeding Enteral nutrition Failure Fatty acids Feasibility studies Feeding Glucose Homeostasis Hospitals Humanities and Social Sciences Humans Illnesses Intensive Care Units Ketone Bodies Ketones Ketosis Metabolism multidisciplinary Pilot Projects Retention Safety Science Science (multidisciplinary) Substrates
ISSN:	2041-1723, 2041-1723
Online-Zugang:	Volltext
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