Assessing the causal relationship between metabolic biomarkers and coronary artery disease by Mendelian randomization studies

The development of coronary artery disease (CAD) is significantly affected by impaired endocrine and metabolic status. Under this circumstance, improved prevention and treatment of CAD may result from knowing the connection between metabolites and CAD. This study aims to delve into the causal relati...

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Bibliographic Details
Published in:	Scientific reports Vol. 14; no. 1; pp. 19034 - 16
Main Authors:	Yang, Kai, Li, Jixin, Hui, Xiaoshan, Wang, Wenru, Liu, Yongmei
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16.08.2024 Nature Publishing Group Nature Portfolio
Subjects:	631/114 631/208 692/163 692/4019 692/499 692/53 Asian People - genetics Benzoic acid Biomarker Biomarkers Biomarkers - blood Blood Cardiovascular disease Coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - genetics Coronary Artery Disease - metabolism Coronary vessels Female Glycerol Heart diseases Heterogeneity Humanities and Social Sciences Humans Interception Male Mendelian randomization Mendelian Randomization Analysis Metabolic pathways Metabolism Metabolites Metabolomics - methods multidisciplinary Plasma metabolites Pleiotropy Prevention Ratios Risk assessment Science Science (multidisciplinary) Sensitivity analysis Spermidine Vein & artery diseases Plasma metabolites Cardiovascular disease Biomarker Mendelian randomization Risk assessment
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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