Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation

Circular RNAs (circRNAs) drive several cellular processes including proliferation, survival, and differentiation. Here, we identified a circRNA hsa_circ_0007813, whose expression was upregulated in bladder cancer. High hsa_circ_0007813 expression was associated with larger tumor size, higher primary...

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Veröffentlicht in:	Cell death & disease Jg. 12; H. 8; S. 778 - 11
Hauptverfasser:	Zhang, Zheyu, Mou, Zezhong, Xu, Chenyang, Wu, Siqi, Dai, Xiyu, Chen, Xinan, Ou, Yuxi, Chen, Yiling, Yang, Chen, Jiang, Haowen
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 07.08.2021 Springer Nature B.V Nature Publishing Group
Schlagworte:	13/1 13/105 13/109 13/2 13/31 13/51 13/89 14 14/19 14/32 14/5 14/63 38 38/39 38/90 45 631/67/2327 631/67/589/1336 631/80/39/2346 631/80/83 631/80/84/2336 Animals Antibodies Autophagy Autophagy - genetics Base Sequence Biochemistry Biomedical and Life Sciences Bladder cancer Cancer Cell Biology Cell Culture Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Circular RNA Disease Progression Gene Expression Regulation, Neoplastic Gene Silencing HEK293 Cells Humans Immunology Insulin-like growth factor II receptors Invasiveness Life Sciences Male Mannose Medical prognosis Mice Mice, Inbred BALB C Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Neoplasm Invasiveness Phagocytosis Phagosomes - metabolism Prognosis Receptor, IGF Type 2 - metabolism Ribonucleic acid RNA RNA, Circular - genetics RNA, Circular - metabolism RNA, Small Interfering - metabolism Survival analysis Tumor cells Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology
ISSN:	2041-4889, 2041-4889
Online-Zugang:	Volltext
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