The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication

Replication of DNA lesions leads to the formation of mutations. In Escherichia coli this process is regulated by the SOS stress response, and requires the mutagenesis proteins UmuC and UmuD'. Analysis of translesion replication using a recently reconstituted in vitro system (Reuven, N. B., Tome...

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Bibliographic Details

Published in:	The Journal of biological chemistry Vol. 274; no. 45; p. 31763
Main Authors:	Reuven, N B, Arad, G, Maor-Shoshani, A, Livneh, Z
Format:	Journal Article
Language:	English
Published:	United States 05.11.1999
Subjects:	Bacterial Proteins - metabolism Base Sequence DNA Polymerase III - metabolism DNA Replication DNA-Binding Proteins - metabolism DNA-Directed DNA Polymerase Electrophoresis, Polyacrylamide Gel Escherichia coli Escherichia coli Proteins Humans Molecular Sequence Data Mutagenesis Rec A Recombinases - metabolism
ISSN:	0021-9258
Online Access:	Get more information
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