Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients

Fanconi anemia (FA) is a rare hereditary disease resulting from an inactivating mutation in the FA/BRCA pathway, critical for the effective repair of DNA interstrand crosslinks (ICLs). The disease is characterized by congenital abnormalities, progressing bone marrow failure, and an increased risk of...

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Bibliographic Details
Published in:	Oncogenesis (New York, NY) Vol. 13; no. 1; pp. 26 - 10
Main Authors:	van Harten, Anne M., Shah, Ronak, de Boer, D. Vicky, Buijze, Marijke, Kreft, Maaike, Song, Ji-Ying, Zürcher, Lisa M., Jacobs, Heinz, Brakenhoff, Ruud H.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.07.2024 Nature Publishing Group
Subjects:	13 13/100 13/106 13/109 13/31 13/51 13/89 14 14/1 14/34 14/56 38 42 45 631/154/1438 631/154/555 631/154/556 631/208/68 631/67/1536 82 82/80 Anemia Apoptosis Breast cancer Cell Biology Chemoradiotherapy Chemotherapy Cisplatin DNA repair Fanconi syndrome Gemcitabine Genetic screening Head & neck cancer Head and neck carcinoma Hemopoiesis Hereditary diseases Human Genetics Internal Medicine Malignancy Medicine Medicine & Public Health Nucleotide analogs Oncology Patients Radiation therapy Ribonucleotide reductase siRNA Squamous cell carcinoma Therapeutic targets Toxicity Tumor cell lines
ISSN:	2157-9024, 2157-9024
Online Access:	Get full text
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