Evaluation of the QuantiFERON SARS-CoV-2 interferon-ɣ release assay in mRNA-1273 vaccinated health care workers

•44 % of vaccinees had INF-ɣ levels above 015 IU/mL in response to stimulation.•100 % of vaccinees showed INF-ɣ levels above 0015 IU/mL in response to stimulation.•More studies are needed to set an appropriate cut-off for this convenient assay. Current studies focus on cellular and humoral immunity...

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Bibliographic Details
Published in:	Journal of virological methods Vol. 298; p. 114295
Main Authors:	Krüttgen, Alexander, Klingel, Hanna, Haase, Gerhard, Haefner, Helga, Imöhl, Matthias, Kleines, Michael
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.12.2021 Published by Elsevier B.V
Subjects:	2019-nCoV Vaccine mRNA-1273 Antibodies, Viral cell-mediated immunity Cellular immunity COVID-19 COVID-19 Vaccines Health Personnel health services hepatitis B Humans humoral immunity Interferon-gamma Release Tests medicine peptides RNA, Messenger - genetics SARS-CoV-2 Serology Severe acute respiratory syndrome coronavirus 2 Vaccination vaccines COVID-19 SARS-CoV-2 Cellular immunity Serology Vaccination
ISSN:	0166-0934, 1879-0984, 1879-0984
Online Access:	Get full text
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