Improving sequence-based modeling of protein families using secondary-structure quality assessment

Abstract Motivation Modeling of protein family sequence distribution from homologous sequence data recently received considerable attention, in particular for structure and function predictions, as well as for protein design. In particular, direct coupling analysis, a method to infer effective pairw...

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Bibliographic Details
Published in:	Bioinformatics (Oxford, England) Vol. 37; no. 22; pp. 4083 - 4090
Main Authors:	Malbranke, Cyril, Bikard, David, Cocco, Simona, Monasson, Rémi
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 18.11.2021 Oxford Publishing Limited (England)
Subjects:	Amino Acid Sequence Availability Bioinformatics Computer graphics Design analysis Functionals Modelling Mutagenesis Original Papers Pattern matching Protein families Protein structure Protein Structure, Secondary Proteins Proteins - chemistry Quality assessment Quality control Secondary structure Sequence Alignment Sequences Structure-function relationships
ISSN:	1367-4803, 1367-4811, 1367-4811
Online Access:	Get full text
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