Improved recognition of native-like protein structures using a family of designed sequences

The goal of the inverse protein folding problem is to identify amino acid sequences that stabilize a given target protein conformation. Methods that attempt to solve this problem have proven useful for protein sequence design. Here we show that the same methods can provide valuable information for p...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 99; no. 2; p. 691
Main Authors:	Koehl, Patrice, Levitt, Michael
Format:	Journal Article
Language:	English
Published:	United States 22.01.2002
Subjects:	Amino Acid Sequence Biophysical Phenomena Biophysics Drug Design Protein Conformation Protein Folding Proteins - chemistry Thermodynamics
ISSN:	0027-8424
Online Access:	Get more information
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