New trends for metal complexes with anticancer activity

Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is, however, severely limited by its toxic side-...

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Veröffentlicht in:	Current opinion in chemical biology Jg. 12; H. 2; S. 197 - 206
Hauptverfasser:	Bruijnincx, Pieter CA, Sadler, Peter J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.04.2008
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology DNA - metabolism Drug Design Enzymes - metabolism Metals - chemistry Metals - metabolism Metals - pharmacology Organometallic Compounds - chemistry Organometallic Compounds - metabolism Organometallic Compounds - pharmacology
ISSN:	1367-5931, 1879-0402
Online-Zugang:	Volltext
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