Network-Based Disease Module Discovery by a Novel Seed Connector Algorithm with Pathobiological Implications

Understanding the genetic basis of complex diseases is challenging. Prior work shows that disease-related proteins do not typically function in isolation. Rather, they often interact with each other to form a network module that underlies dysfunctional mechanistic pathways. Identifying such disease...

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Bibliographic Details
Published in:Journal of molecular biology Vol. 430; no. 18; pp. 2939 - 2950
Main Authors: Wang, Rui-Sheng, Loscalzo, Joseph
Format: Journal Article
Language:English
Published: England Elsevier Ltd 14.09.2018
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ISSN:0022-2836, 1089-8638, 1089-8638
Online Access:Get full text
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