Nucleic Acid Testing to Detect HBV Infection in Blood Donors

In this study involving 3.7 million blood donors, nucleic acid testing identified 9 donors with HBV infection who were not identified by routine serologic testing. The single triplex assay also identified 2 donors with HIV and 15 with HCV. The transfusion of blood containing hepatitis B surface anti...

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Vydané v:	The New England journal of medicine Ročník 364; číslo 3; s. 236 - 247
Hlavní autori:	Stramer, Susan L, Wend, Ulrike, Candotti, Daniel, Foster, Gregory A, Hollinger, F. Blaine, Dodd, Roger Y, Allain, Jean-Pierre, Gerlich, Wolfram
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Waltham, MA Massachusetts Medical Society 20.01.2011
Predmet:	Biological and medical sciences Blood Donors Disease Transmission, Infectious DNA, Viral - blood Follow-Up Studies General aspects Genotype Hepatitis B - diagnosis Hepatitis B Antibodies - blood Hepatitis B Core Antigens - blood Hepatitis B Surface Antigens - blood Hepatitis B Surface Antigens - immunology Hepatitis B virus - genetics Hepatitis B virus - isolation & purification HIV - genetics HIV - isolation & purification Human viral diseases Humans Infectious diseases Medical sciences Nucleic Acid Amplification Techniques Phylogeny Polymerase Chain Reaction Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine RNA, Viral - blood Sexual Partners Testing laboratories Tropical diseases Viral diseases Viral hepatitis Viral Load Infection Human Viral hepatitis B Medicine Viral disease Digestive diseases Hepatic disease Medical screening Detection Nucleic acid Blood donor
ISSN:	0028-4793, 1533-4406, 1533-4406
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