Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target?

Introduction: Central sensitization is a form of maladaptive neuroplasticity underlying many chronic pain disorders, including neuropathic pain, fibromyalgia, whiplash, headache, chronic pelvic pain syndrome and some forms of osteoarthritis, low back pain, epicondylitis, shoulder pain and cancer pai...

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Bibliographic Details
Published in:	Expert opinion on therapeutic targets Vol. 19; no. 4; pp. 565 - 576
Main Authors:	Nijs, Jo, Meeus, Mira, Versijpt, Jan, Moens, Maarten, Bos, Inge, Knaepen, Kristel, Meeusen, Romain
Format:	Journal Article
Language:	English
Published:	England Informa UK, Ltd 01.04.2015 Informa Healthcare
Subjects:	Animals Brain-Derived Neurotrophic Factor - metabolism Central Nervous System Sensitization - physiology chronic pain Chronic Pain - physiopathology Chronic Pain - therapy Combined Modality Therapy descending inhibition exercise Humans long-term potentiation Molecular Targeted Therapy Neuralgia - physiopathology Neuralgia - therapy Neuronal Plasticity - physiology neuropathic pharmacotherapy Signal Transduction - physiology neuropathic exercise chronic pain descending inhibition pharmacotherapy long-term potentiation
ISSN:	1472-8222, 1744-7631, 1744-7631
Online Access:	Get full text
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