Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling

The mechanisms of receptor- and cell-specific effects of the adrenal corticosteroid hormones via mineralo- (MRs) and glucocorticoid receptors (GRs) are still poorly understood. Because the expression levels of two splice variants of the steroid receptor coactivator-1 (SRC-1) 1a and 1e, can differ si...

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Bibliographic Details
Published in:	Endocrinology (Philadelphia) Vol. 146; no. 3; p. 1438
Main Authors:	Meijer, O C, Kalkhoven, E, van der Laan, S, Steenbergen, P J, Houtman, S H, Dijkmans, T F, Pearce, D, de Kloet, E R
Format:	Journal Article
Language:	English
Published:	United States 01.03.2005
Subjects:	Alternative Splicing Animals Blotting, Western Cell Line Cell Line, Tumor Corticosterone - metabolism Genes, Reporter Histone Acetyltransferases Humans In Situ Hybridization Ligands Models, Biological Nuclear Receptor Coactivator 1 Plasmids - metabolism Polymerase Chain Reaction Promoter Regions, Genetic Protein Structure, Tertiary Rats Rats, Wistar Receptors, Steroid - metabolism RNA, Messenger - metabolism Signal Transduction Transcription Factors - biosynthesis Transcription Factors - chemistry Transcription Factors - genetics Transcription, Genetic Transfection
ISSN:	0013-7227
Online Access:	Get more information
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