New Insights and Potential Therapeutic Interventions in Metabolic Diseases

Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this revi...

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Bibliographic Details
Published in:International journal of molecular sciences Vol. 24; no. 13; p. 10672
Main Authors: Clemente-Suárez, Vicente Javier, Martín-Rodríguez, Alexandra, Redondo-Flórez, Laura, López-Mora, Clara, Yáñez-Sepúlveda, Rodrigo, Tornero-Aguilera, José Francisco
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 26.06.2023
MDPI
Subjects:
Antioxidants
Behavior
Body fat
Cardiovascular disease
Care and treatment
Development and progression
Diabetes
Diet
Disease prevention
DNA methylation
Epigenesis, Genetic
Epigenetic inheritance
Epigenetics
Exercise
Gastrointestinal Microbiome
Gene expression
Glucose
Humans
Insulin resistance
Lipids
Liver diseases
Magnetic resonance imaging
Metabolic Diseases - metabolism
Metabolic Diseases - therapy
Metabolic disorders
Nutrition research
Obesity
Oxidative stress
Physical fitness
Review
Type 2 diabetes
Spain
genetic
microbiota
nutrition
single-cell transcriptomics
advanced imaging techniques
cell-based therapies
psychology
gut
epigenetics
physical activity
ISSN:1422-0067, 1661-6596, 1422-0067
Online Access:Get full text
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Summary:Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made.
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ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms241310672