Characterization of novel inhibitors of histone acetyltransferases

Modification of proteins by histone acetyltransferases (HAT) or histone deacetylases plays an important role in the control of gene expression, and its dysregulation has been linked to malignant transformation and other diseases. Although histone deacetylase inhibitors have been extensively studied...

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Veröffentlicht in:	Molecular cancer therapeutics Jg. 6; H. 9; S. 2391
Hauptverfasser:	Eliseeva, Elena D, Valkov, Vassil, Jung, Manfred, Jung, Mira O
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2007
Schlagworte:	Acetylation Anacardic Acids - chemical synthesis Anacardic Acids - chemistry Anacardic Acids - pharmacology Blotting, Western Cell Proliferation - drug effects Cyclin-Dependent Kinase Inhibitor p21 - metabolism Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Histone Acetyltransferases - antagonists & inhibitors Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Histones - metabolism Humans Luciferases - metabolism p300-CBP Transcription Factors - antagonists & inhibitors p300-CBP Transcription Factors - genetics p300-CBP Transcription Factors - metabolism Promoter Regions, Genetic Transcription, Genetic Transcriptional Activation Tumor Cells, Cultured
ISSN:	1535-7163
Online-Zugang:	Weitere Angaben
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