Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

The emergence and spread of antimicrobial resistance in Neisseria gonorrhoeae is seriously threatening the treatment and control of gonorrhea globally. Novel treatment options are essential, coupled with appropriate methods to pharmacodynamically examine the efficacy and resistance emergence of thes...

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Veröffentlicht in:	Frontiers in pharmacology Jg. 13; S. 1035841
Hauptverfasser:	Jacobsson, Susanne, Golparian, Daniel, Oxelbark, Joakim, Wicha, Wolfgang W., da Costa, Renata Maria Augusto, Franceschi, Francois, Brown, David, Louie, Arnold, Gelone, Steven P., Drusano, George, Unemo, Magnus
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Frontiers Media S.A 14.11.2022
Schlagworte:	antimicrobial treatment gonorrhea hollow fiber infection model lefamulin Neisseria gonorrhoeae pharmacodynamics pharmacokinetics Pharmacology
ISSN:	1663-9812, 1663-9812
Online-Zugang:	Volltext
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