Implications of new monoclonal antibodies and the crystal structure of the TSH receptor for the treatment and management of thyroid diseases

Autoantibodies to the thyroid-stimulating hormone receptor (TSHR) cause the hyperthyroidism of Graves ’ disease and contribute to Graves ’ eye signs. Human monoclonal TSHR autoantibodies prepared from patients ’ lymphocytes have important clinical applications in terms of their ability to stimulate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomarkers in medicine Jg. 2; H. 6; S. 567 - 576
Hauptverfasser:	Rees Smith, Bernard, Sanders, Jane, Furmaniak, Jadwiga
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Future Medicine Ltd 01.12.2008
Schlagworte:	Autoantibodies Autoimmunity Binding sites Cancer Care and treatment Crystals Disease Eye diseases Graves ’ disease Hormones Hypothyroidism Immune system Inventors Lymphocytes Molecular weight Monoclonal antibodies Proteins Structure thyroid Thyroid diseases Thyroid gland thyroid-stimulating hormone Thyrotropin TSH TSH receptor
ISSN:	1752-0363, 1752-0371, 1752-0371
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!