Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo

Bisphosphonates (such as risedronate and zoledronate) are widely used inhibitors of bone resorption. Despite their in vitro antiproliferative effects in various cancer cells, bisphosphonates have not exhibited significant antitumor efficacy in animal models of visceral cancer, which may be due to th...

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Bibliographic Details

Published in:	Clinical cancer research Vol. 12; no. 9; p. 2862
Main Authors:	Wakchoure, Savita, Merrell, Melinda A, Aldrich, Wayne, Millender-Swain, Telisha, Harris, Kevin W, Triozzi, Pierre, Selander, Katri S
Format:	Journal Article
Language:	English
Published:	United States 01.05.2006
Subjects:	Animals Cell Division - drug effects Cell Line, Tumor Diphosphonates - pharmacology Diphosphonates - therapeutic use Disease Models, Animal Etidronic Acid - analogs & derivatives Etidronic Acid - therapeutic use Imidazoles - therapeutic use Mesothelioma - drug therapy Mesothelioma - pathology Mice Phosphorylation Risedronate Sodium
ISSN:	1078-0432
Online Access:	Get more information
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