Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo

Bisphosphonates (such as risedronate and zoledronate) are widely used inhibitors of bone resorption. Despite their in vitro antiproliferative effects in various cancer cells, bisphosphonates have not exhibited significant antitumor efficacy in animal models of visceral cancer, which may be due to th...

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Veröffentlicht in:	Clinical cancer research Jg. 12; H. 9; S. 2862
Hauptverfasser:	Wakchoure, Savita, Merrell, Melinda A, Aldrich, Wayne, Millender-Swain, Telisha, Harris, Kevin W, Triozzi, Pierre, Selander, Katri S
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.05.2006
Schlagworte:	Animals Cell Division - drug effects Cell Line, Tumor Diphosphonates - pharmacology Diphosphonates - therapeutic use Disease Models, Animal Etidronic Acid - analogs & derivatives Etidronic Acid - therapeutic use Imidazoles - therapeutic use Mesothelioma - drug therapy Mesothelioma - pathology Mice Phosphorylation Risedronate Sodium
ISSN:	1078-0432
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