Orally Inhaled Drug Particle Transport in Computerized Models of Laryngotracheal Stenosis

Adjuvant management for laryngotracheal stenosis (LTS) may involve inhaled corticosteroids, but metered dose inhalers are designed for pulmonary drug delivery. Comprehensive analyses of drug particle deposition efficiency for orally inhaled corticosteroids in the stenosis of LTS subjects are lacking...

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Vydané v:	Otolaryngology-head and neck surgery Ročník 164; číslo 4; s. 829
Hlavní autori:	Frank-Ito, Dennis Onyeka, Cohen, Seth Morris
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.04.2021
Predmet:	Administration, Inhalation Administration, Oral Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - chemistry Computer Simulation Humans Hydrodynamics Laryngostenosis - complications Laryngostenosis - drug therapy Models, Anatomic Particle Size Tracheal Stenosis - complications Tracheal Stenosis - drug therapy subglottic stenosis tracheal stenosis spacer chamber metered dose inhalers laryngotracheal stenosis computational fluid dynamics airflow particle transport inhaled corticosteroids
ISSN:	1097-6817, 1097-6817
On-line prístup:	Zistit podrobnosti o prístupe
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