Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans

Metabolism of 25-hydroxyvitamin D3 (25OHD3) plays a central role in regulating the biologic effects of vitamin D in the body. Although cytochrome P450-dependent hydroxylation of 25OHD3 has been extensively investigated, limited information is available on the conjugation of 25OHD3 In this study, we...

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Bibliographic Details

Published in:	Drug metabolism and disposition Vol. 46; no. 4; p. 367
Main Authors:	Wong, Timothy, Wang, Zhican, Chapron, Brian D, Suzuki, Mizuki, Claw, Katrina G, Gao, Chunying, Foti, Robert S, Prasad, Bhagwat, Chapron, Alenka, Calamia, Justina, Chaudhry, Amarjit, Schuetz, Erin G, Horst, Ronald L, Mao, Qingcheng, de Boer, Ian H, Thornton, Timothy A, Thummel, Kenneth E
Format:	Journal Article
Language:	English
Published:	01.04.2018
ISSN:	1521-009X, 1521-009X
Online Access:	Get more information
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