Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans

Metabolism of 25-hydroxyvitamin D3 (25OHD3) plays a central role in regulating the biologic effects of vitamin D in the body. Although cytochrome P450-dependent hydroxylation of 25OHD3 has been extensively investigated, limited information is available on the conjugation of 25OHD3 In this study, we...

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Vydané v:	Drug metabolism and disposition Ročník 46; číslo 4; s. 367
Hlavní autori:	Wong, Timothy, Wang, Zhican, Chapron, Brian D, Suzuki, Mizuki, Claw, Katrina G, Gao, Chunying, Foti, Robert S, Prasad, Bhagwat, Chapron, Alenka, Calamia, Justina, Chaudhry, Amarjit, Schuetz, Erin G, Horst, Ronald L, Mao, Qingcheng, de Boer, Ian H, Thornton, Timothy A, Thummel, Kenneth E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	01.04.2018
ISSN:	1521-009X, 1521-009X
On-line prístup:	Zistit podrobnosti o prístupe
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